SCHEMBL4645331

SCHEMBL4645331

[CH2]CC(=O)OC(=O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
F2 P00734 1/20 0.52
TDP1 Q9NUW8 4/20 0.48
TSHR P16473 5/20 0.48
KMT2A Q03164 4/20 0.47
MAPK1 P28482 2/20 0.47
HIF1A Q16665 1/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A3 Q01959 1/20 0.47
ALDH1A1 P00352 5/20 0.46
TP53 P04637 1/20 0.44
MAPT P10636 3/20 0.42
POLB P06746 1/20 0.42
PRSS1 P07477 1/20 0.42
CTSG P08311 1/20 0.42
CTRB1 P17538 1/20 0.42
CMA1 P23946 1/20 0.42
CES1 P23141 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
KDM4E B2RXH2 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4647395 0.84 LMNA (0.48) LMNAF2TDP1TSHRKMT2A
SCHEMBL9318015 0.83 LMNA (0.56) LMNAF2TDP1TSHRKMT2A
SCHEMBL2611692 0.83 TSHR (0.58) LMNAF2TDP1TSHRKMT2A
SCHEMBL4645742 0.81 TDP1 (0.47) LMNAF2TDP1TSHRKMT2A
SCHEMBL3994317 0.81 LMNA (0.54) LMNAF2TDP1TSHRKMT2A
SCHEMBL242716 0.81 LMNA (0.57) LMNAF2TDP1TSHRKMT2A
SCHEMBL15485653 0.81 LMNA (0.54) LMNAF2TDP1TSHRKMT2A
Water SCHEMBL21440321 0.81 LMNA (0.54) LMNAF2TDP1TSHRKMT2A
SCHEMBL3994318 0.81 LMNA (0.54) LMNAF2TDP1TSHRKMT2A
SCHEMBL27192192 0.81 LMNA (0.54) LMNAF2TDP1TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4684664-A BACTERICIDES, FUNGICIDES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-08-04 US claimed
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed
EP-0675127-A1 QUINOLINECARBOXYLIC ACID DERIVATIVE AND PROCESS FOR PRODUCING THE SAME NIPPON SHINYAKU COMPANY, LIMITED (JP) 1995-10-04 EP disclosed
US-4551467-A Vasodilating cyanoalkyl esters of 1,4-dihydropyridines BAYER AKTIENGESELLSCHAFT (DE) 1985-11-05 US disclosed
US-4496480-A Isothiazolazo dyes having coupling components which are free from unsaturated aliphatic radicals BASF AKTIENGESELLSCHAFT (DE) 1985-01-29 US disclosed