SCHEMBL4645400

SCHEMBL4645400

O=C(CCCCl)C(=O)Cc1ccc(Cl)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.44
TDP1 Q9NUW8 1/20 0.44
EGFR P00533 1/20 0.44
ERBB2 P04626 1/20 0.44
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
CTBP2 P56545 1/20 0.43
LMNA P02545 1/20 0.42
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
FFAR2 O15552 1/20 0.42
KMT2A Q03164 4/20 0.41
MEN1 O00255 3/20 0.41
PIK3CA P42336 2/20 0.41
MAPT P10636 2/20 0.41
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4644594 0.95 HDAC3 (0.44) L3MBTL1TDP1EGFRERBB2NPC1
SCHEMBL4645506 0.89 EGFR (0.46) L3MBTL1EGFRERBB2NPC1RAB9A
SCHEMBL4642197 0.85 L3MBTL1 (0.46) L3MBTL1TDP1EGFRERBB2NPC1
SCHEMBL4643975 0.84 GAA (0.43) TDP1EGFRERBB2NPC1RAB9A
SCHEMBL28754829 0.84 L3MBTL1 (0.42) L3MBTL1TDP1EGFRERBB2NPC1
SCHEMBL4642061 0.84 L3MBTL1 (0.45) L3MBTL1TDP1EGFRERBB2NPC1
SCHEMBL4644050 0.83 CES1 (0.65) L3MBTL1TDP1CES2CES1KMT2A
SCHEMBL6222420 0.83 VNN1 (0.47) L3MBTL1TDP1EGFRERBB2NPC1
SCHEMBL4646613 0.81 EGFR (0.46) L3MBTL1TDP1EGFRERBB2NPC1
SCHEMBL4644802 0.80 EGFR (0.49) L3MBTL1TDP1EGFRERBB2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100519671-C Film-forming polymer and antifouling paint JOTUN AS (NO) 2009-07-29 CN disclosed
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
CN-1643085-A Film-forming polymer and antifouling paint JOTUN AS (NO) 2005-07-20 CN disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed