Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | HPGD | P15428 | 5/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.63 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.63 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13080235 | 1.00 | ALDH1A1 (0.63) | ALDH1A1MAPTHPGDNPSR1LMNA | |
| SCHEMBL600478 | 0.83 | ALDH1A1 (0.68) | ALDH1A1MAPTHPGDNPSR1LMNA | |
| SCHEMBL9330897 | 0.83 | ALDH1A1 (0.68) | ALDH1A1MAPTHPGDNPSR1LMNA | |
| SCHEMBL600479 | 0.83 | ALDH1A1 (0.68) | ALDH1A1MAPTHPGDNPSR1LMNA | |
| Water SCHEMBL9776234 | 0.81 | ALDH1A1 (0.66) | ALDH1A1MAPTHPGDNPSR1LMNA | |
| Water SCHEMBL9776229 | 0.81 | ALDH1A1 (0.66) | ALDH1A1MAPTHPGDNPSR1LMNA | |
| SCHEMBL7516071 | 0.79 | ALDH1A1 (0.63) | ALDH1A1MAPTHPGDNPSR1LMNA | |
| SCHEMBL7516062 | 0.79 | ALDH1A1 (0.63) | ALDH1A1MAPTHPGDNPSR1LMNA | |
| Zinc Ion SCHEMBL9776224 | 0.78 | ALDH1A1 (0.61) | ALDH1A1MAPTHPGDNPSR1LMNA | |
| SCHEMBL9845628 | 0.78 | ALDH1A1 (0.61) | ALDH1A1MAPTHPGDNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957459-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063702-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |