SCHEMBL4646407

SCHEMBL4646407

CC(=O)OC(=O)COc1ccc(F)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
MAOB P27338 2/20 0.49
KMT2A Q03164 5/20 0.48
MEN1 O00255 4/20 0.48
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
GAA P10253 2/20 0.47
LMNA P02545 2/20 0.47
AOC2 O75106 1/20 0.47
DAO P14920 1/20 0.47
MAOA P21397 1/20 0.47
HTT P42858 2/20 0.47
ALDH1A1 P00352 1/20 0.47
PKM P14618 1/20 0.47
FKBP1A P62942 1/20 0.45
MAPK1 P28482 1/20 0.44
CASP3 P42574 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3913184 0.82 PTGS2 (0.58) MAPTSMN1; SMN2MAOBKMT2AMEN1
SCHEMBL4646403 0.82 MAPT (0.48) MAPTSMN1; SMN2MAOBKMT2AMEN1
SCHEMBL264347 0.81 ALOX15 (0.59) MAPTSMN1; SMN2KMT2AMEN1NPC1
SCHEMBL5114126 0.81 MAPT (0.58) MAPTSMN1; SMN2KMT2AMEN1NPC1
SCHEMBL4645866 0.81 MAPT (0.48) MAPTSMN1; SMN2MAOBKMT2AMEN1
SCHEMBL5107568 0.81 MAOB (0.54) MAPTSMN1; SMN2MAOBKMT2AMEN1
SCHEMBL4645871 0.81 MAPT (0.47) MAPTSMN1; SMN2MAOBKMT2AMEN1
SCHEMBL9327188 0.81 PLA2G4B (0.58) HTTPKMMAPK1
SCHEMBL4642322 0.80 MAPT (0.47) MAPTSMN1; SMN2MAOBKMT2AMEN1
SCHEMBL1524512 0.79 SMN1; SMN2 (0.65) SMN1; SMN2MAOBKMT2AMEN1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed