SCHEMBL4646765

SCHEMBL4646765

C[N+](C)(C)CC(O)(c1ccc(N)cc1)P(=O)(O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 4/20 0.46
EPHX2 P34913 1/20 0.35
PTGS1 P23219 2/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C19 P33261 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
PKM P14618 1/20 0.33
APEX1 P27695 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PGK1 P00558 1/20 0.33
PGK2 P07205 1/20 0.33
ESRRG P62508 1/20 0.33
NPC1 O15118 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8149759 0.83 PTPN1 (0.46) FDPSMEN1KMT2AALDH1A1POLB
SCHEMBL11029750 0.78 PTPRC (0.43) MEN1KMT2AALDH1A1MAPTPOLB
SCHEMBL8149509 0.72 PGK1 (0.43) FDPSMEN1KMT2APGK1PGK2
SCHEMBL4094823 0.70 FDPS (0.53) FDPSPTGS1MEN1KMT2AMAPT
Water SCHEMBL5163400 0.69 FDPS (0.52) FDPSPTGS1MEN1KMT2AMAPT
SCHEMBL15187676 0.69 FDPS (0.47) FDPSEPHX2PTGS1MEN1KMT2A
SCHEMBL2637396 0.69 FDPS (0.47) FDPSEPHX2PTGS1MEN1KMT2A
SCHEMBL8154833 0.68 PGK1 (0.40) PGK1PGK2PTPN5
SCHEMBL2030830 0.68 FDPS (0.47) FDPSEPHX2PTGS1ALDH1A1CYP1A2
Trimethylammonium SCHEMBL27751864 0.68 FDPS (0.47) FDPSEPHX2PTGS1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250375529-A1 PHOSPHORYLCHOLINE-TUFTSIN CONJUGATE FOR TREATING OCULAR INFLAMMATION Tarsier Pharma Ltd (IL) 2025-12-11 US claimed
EP-2953978-B1 PHOSPHORYLCHOLINE CONJUGATES AND USES THEREOF TPCERA LTD (IL) 2024-10-23 EP claimed
WO-2024028192-A1 USE OF CONJUGATES OF HUMAN SERUM ALBUMIN AND PHOSPHOCHOLINE FOR BLOCKING C-REACTIVE PROTEIN PENTRACOR GMBH (DE) 2024-02-08 WO claimed
US-20230338461-A1 PHOSPHORYLCHOLINE CONJUGATES AND USES THEREOF TPCERA LTD. (IL) 2023-10-26 US claimed
US-11696935-B2 Phosphorylcholine conjugates and uses thereof TPCERA LTD. (IL) 2023-07-11 US claimed
US-11458186-B2 Phosphorylcholine conjugates and uses thereof TPCERA LTD. (IL) 2022-10-04 US claimed
US-20210161992-A1 PHOSPHORYLCHOLINE CONJUGATES AND USES THEREOF TPCERA LTD. (IL) 2021-06-03 US claimed
US-20210069284-A1 PHOSPHORYLCHOLINE CONJUGATES AND USES THEREOF TPCERA LTD. (IL) 2021-03-11 US claimed
US-10842844-B2 Phosphorylcholine conjugates and uses thereof TPCERA LTD. (IL) 2020-11-24 US claimed
US-20180353566-A1 PHOSPHORYLCHOLINE CONJUGATES AND USES THEREOF TPCERA LTD. (IL) 2018-12-13 US claimed
US-9987372-B2 Phosphorylcholine conjugates and uses thereof TPCERA LTD. (IL) 2018-06-05 US claimed
US-20250375529-A1 PHOSPHORYLCHOLINE-TUFTSIN CONJUGATE FOR TREATING OCULAR INFLAMMATION Tarsier Pharma Ltd (IL) 2025-12-11 US disclosed
US-12390569-B2 Simplified regeneration of apheresis columns PENTRACOR GMBH (DE) 2025-08-19 US disclosed
US-12350308-B2 Phosphorylcholine conjugates and uses thereof TPCERA LTD. (IL) 2025-07-08 US disclosed
US-20250186535-A1 OPHTALMIC COMPOSITIONS AND METHODS OF USING SAME TARSIER PHARMA LTD. (IL) 2025-06-12 US disclosed
WO-2014122646-A1 PHOSPHORYLCHOLINE CONJUGATES AND USES THEREOF TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD. (IL) 2014-08-14 WO disclosed
EP-1962923-B1 USE OF A MATRIX FOR REMOVING C-REACTIVE PROTEIN FROM BIOLOGICAL LIQUIDS PENTRACOR GMBH (DE) 2013-05-01 EP disclosed
EP-1962923-A1 USE OF A MATRIX FOR REMOVING C-REACTIVE PROTEIN FROM BIOLOGICAL LIQUIDS BETA V3 GmbH (DE) 2008-09-03 EP disclosed
WO-2007076844-A1 USE OF A MATRIX FOR REMOVING C-REACTIVE PROTEIN FROM BIOLOGICAL LIQUIDS BETA V3 GMBH (DE) 2007-07-12 WO disclosed
US-5003065-A Phosphorus-containing Benzo Crown Ethers STATE UNIVERSITY OF NEW YORK, STATE UNIVERSITY PLAZA, A CORP OF NY. 1991-03-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250186535-A1 OPHTALMIC COMPOSITIONS AND METHODS OF USING SAME PHOSPHO1, PDE6C, CHKA FDPS 4273/4885EPHX2 2000/4885PTGS1 991/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.