Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL429871 | 1.00 | NPC1 (0.39) | NPC1HTTRAB9AMAOBMEN1 | |
| SCHEMBL10280577 | 0.80 | MAPT (0.48) | NPC1HTTRAB9AMEN1ALDH1A1 | |
| SCHEMBL428525 | 0.80 | MAPT (0.48) | NPC1HTTRAB9AMEN1ALDH1A1 | |
| SCHEMBL10280041 | 0.79 | MAPT (0.43) | NPC1HTTRAB9AALDH1A1MAPT | |
| SCHEMBL428614 | 0.79 | MAPT (0.43) | NPC1HTTRAB9AALDH1A1MAPT | |
| SCHEMBL427471 | 0.77 | PBRM1 (0.32) | — | |
| SCHEMBL429932 | 0.76 | MAOA (0.41) | MEN1ALDH1A1MAPTKMT2AMAOA | |
| SCHEMBL428522 | 0.76 | NFE2L2 (0.30) | — | |
| SCHEMBL430429 | 0.76 | KDM4E (0.37) | — | |
| SCHEMBL10280051 | 0.76 | NFE2L2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065064-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-03-15 | — | — | US | disclosed |
| WO-2010069834-A1 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065064-A1 | NOVEL HERBICIDES | DDT, CYP1B1, CYP4X1 | NPC1 4593/4885HTT 524/4885RAB9A 3219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.