Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | TACR2 | P21452 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SHBG | P04278 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | TST | Q16762 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7618724 | 1.00 | PTGS2 (0.62) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL9145508 | 0.92 | NPC1 (0.55) | PTGS2CYP3A4ESR1GPR84NPC1 | |
| SCHEMBL27566011 | 0.89 | PTGS2 (0.55) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| Diethanolamine SCHEMBL11504135 | 0.87 | PTGS2 (0.49) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| Diethanolamine SCHEMBL11504183 | 0.87 | PTGS2 (0.49) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL5138127 | 0.87 | PTGS2 (0.53) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| Diethanolamine SCHEMBL11504678 | 0.85 | PTGS2 (0.47) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL11577734 | 0.85 | PTGS2 (0.47) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL542182 | 0.83 | CYP3A4 (0.46) | PTGS2CYP3A4ESR1ALDH1A1HIF1A | |
| SCHEMBL2420912 | 0.83 | CYP3A4 (0.50) | PTGS2CYP3A4ESR1ALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244756-B2 | HIGH REFRACTIVE INDEX PRESSURE-SENSITIVE ADHESIVES | 3M INNOVATIVE PROPERTIES CO (US) | 2008-08-20 | — | — | EP | disclosed |
| US-7335425-B2 | High refractive index pressure-sensitive adhesives | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-02-26 | — | — | US | disclosed |
| US-20070264517-A1 | HIGH REFRACTIVE INDEX PRESSURE-SENSITIVE ADHESIVES | 3M INNOVATIVE PROPERTIES COMPANY | 2007-11-15 | — | — | US | disclosed |
| US-7166686-B2 | High refractive index pressure-sensitive adhesives | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-01-23 | — | — | US | disclosed |
| US-20050272949-A1 | High refractive index pressure-sensitive adhesives | 3M INNOVATIVE PROPERTIES COMPANY | 2005-12-08 | — | — | US | disclosed |
| EP-1244756-B1 | HIGH REFRACTIVE INDEX PRESSURE-SENSITIVE ADHESIVES | 3M INNOVATIVE PROPERTIES CO (US) | 2004-10-27 | — | — | EP | disclosed |
| US-20040091729-A1 | High refractive index pressure-sensitive adhesives | 3M INNOVATIVE PROPERTIES COMPANY | 2004-05-13 | — | — | US | disclosed |
| US-6663978-B1 | Polymer of an acrylic or methacrylic acid ester containing a substituted or an unsubstituted aromatic moiety | 3M INNOVATIVE PROPERTIES COMPANY | 2003-12-16 | — | — | US | disclosed |
| EP-0980532-B1 | OPTICAL PRODUCT PREPARED FROM HIGH INDEX OF REFRACTION BROMINATED MONOMERS | MINNESOTA MINING & MFG (US) | 2003-04-02 | — | — | EP | disclosed |
| EP-0980398-B1 | CHEMICAL COMPOSITION AND POLYMERS AND POLYMERIC MATERIALS DERIVED THEREFROM | MINNESOTA MINING & MFG (US) | 2002-11-27 | — | — | EP | disclosed |
| EP-0994844-B1 | HIGH INDEX OF REFRACTION MONOMERS | MINNESOTA MINING & MFG (US) | 2002-07-31 | — | — | EP | disclosed |
| US-6355754-B1 | 4,6-DIBROMO-2-ALKYL PHENYL ACRYLATE AND AROMATIC (METH)ACRYLATE COMONOMERS; OPTICS, LOW MELTING | 3M INNOVATIVE PROPERTIES COMPANY | 2002-03-12 | — | — | US | disclosed |
| WO-2001030933-A1 | HIGH REFRACTIVE INDEX PRESSURE-SENSITIVE ADHESIVES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2001-05-03 | — | — | WO | disclosed |
| EP-0994844-A1 | HIGH INDEX OF REFRACTION MONOMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-04-26 | — | — | EP | disclosed |
| EP-0980398-A1 | CHEMICAL COMPOSITION AND POLYMERS AND POLYMERIC MATERIALS DERIVED THEREFROM | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-02-23 | — | — | EP | disclosed |
| EP-0980532-A1 | OPTICAL PRODUCT PREPARED FROM HIGH INDEX OF REFRACTION BROMINATED MONOMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-02-23 | — | — | EP | disclosed |
| US-5932626-A | BRIGHTNESS PROMOTING FILM | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-08-03 | — | — | US | disclosed |
| WO-1998050340-A1 | HIGH INDEX OF REFRACTION MONOMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-11-12 | — | — | WO | disclosed |
| WO-1998050805-A1 | OPTICAL PRODUCT PREPARED FROM HIGH INDEX OF REFRACTION BROMINATED MONOMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-11-12 | — | — | WO | disclosed |
| WO-1998050442-A1 | CHEMICAL COMPOSITION AND POLYMERS AND POLYMERIC MATERIALS DERIVED THEREFROM | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272949-A1 | High refractive index pressure-sensitive adhesives | ICAM1, CDH1, EPCAM | PTGS2 1989/4885CYP3A4 4662/4885ESR1 1617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.