Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18429036 | 0.89 | GABRA5 (0.40) | SLC6A2SLC6A4EPHX1GABRA5GABRB2 | |
| SCHEMBL5800001 | 0.88 | NPSR1 (0.44) | SLC6A2SLC6A4GAANPSR1TSHR | |
| SCHEMBL15284107 | 0.84 | GAA (0.39) | GAANPSR1ALDH1A1 | |
| SCHEMBL75481 | 0.77 | TDP1 (0.39) | SLC6A2SLC6A4GAANPSR1TSHR | |
| SCHEMBL13209101 | 0.77 | GABRA5 (0.40) | GABRA5GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL2276331 | 0.73 | SLC6A4 (0.39) | SLC6A2SLC6A4GAANPSR1 | |
| SCHEMBL2276334 | 0.73 | SLC6A4 (0.39) | SLC6A2SLC6A4GAANPSR1 | |
| SCHEMBL16795227 | 0.72 | SLC6A4 (0.44) | SLC6A2SLC6A4EPHX1GABRA5GABRB2 | |
| SCHEMBL17337970 | 0.71 | ALDH1A1 (0.43) | SLC6A2SLC6A4TSHRPMP22ALDH1A1 | |
| SCHEMBL3205284 | 0.71 | ALDH1A1 (0.43) | SLC6A2SLC6A4TSHRPMP22ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685102-A4 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD (KR) | 2008-08-20 | — | — | EP | disclosed |
| EP-1685102-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG Life Sciences Ltd. (KR) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005047251-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD. (KR) | 2005-05-26 | — | — | WO | disclosed |