SCHEMBL4647100

SCHEMBL4647100

[CH2]CC(=O)OC(=O)Cc1ccc(Cl)cc1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.49
L3MBTL1 Q9Y468 5/20 0.45
MAPT P10636 3/20 0.45
TSHR P16473 2/20 0.45
KMT2A Q03164 1/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 3/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
CTBP2 P56545 1/20 0.43
TDP1 Q9NUW8 2/20 0.42
KLK7 P49862 1/20 0.42
GAA P10253 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8855417 0.90 POLB (0.56) POLBL3MBTL1MAPTTSHRKMT2A
SCHEMBL4644797 0.86 POLB (0.46) POLBL3MBTL1MAPTTSHRKMT2A
SCHEMBL4641821 0.83 POLB (0.50) POLBL3MBTL1MAPTTSHRKMT2A
SCHEMBL4644174 0.83 L3MBTL1 (0.44) POLBL3MBTL1MAPTTSHRKMT2A
SCHEMBL4642443 0.81 KMT2A (0.47) POLBL3MBTL1KMT2AALDH1A1RAB9A
SCHEMBL4641557 0.81 AKR1B1 (0.56) L3MBTL1TSHRKMT2AALDH1A1LMNA
SCHEMBL13360707 0.80 POLB (0.51) POLBL3MBTL1MAPTTSHRKMT2A
SCHEMBL4641827 0.79 POLB (0.54) POLBL3MBTL1MAPTTSHRKMT2A
SCHEMBL4642521 0.79 KMT2A (0.55) POLBL3MBTL1MAPTKMT2AALDH1A1
SCHEMBL15514077 0.79 POLB (0.53) POLBL3MBTL1MAPTTSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed