Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | USP10 | Q14694 | 1/20 | 0.47 |
| ▸ | USP7 | Q93009 | 1/20 | 0.47 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | DTYMK | P23919 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16953719 | 0.87 | ATM (0.58) | TDP1ATMMAPTUSP10USP7 | |
| SCHEMBL621197 | 0.86 | TDP1 (0.52) | TDP1ATMMAPTUSP10USP7 | |
| SCHEMBL29380481 | 0.84 | ATM (0.55) | TDP1ATMMAPTUSP10USP7 | |
| SCHEMBL14577163 | 0.84 | ATM (0.55) | TDP1ATMMAPTUSP10USP7 | |
| SCHEMBL357813 | 0.84 | DTYMK (0.62) | TDP1ATMTTRALDH1A1DTYMK | |
| SCHEMBL12789525 | 0.83 | HSPB1 (0.51) | TDP1ATMMAPTTTRALDH1A1 | |
| SCHEMBL16957125 | 0.83 | TDP1 (0.53) | TDP1ATMMAPTUSP10USP7 | |
| SCHEMBL2718272 | 0.82 | ATM (0.49) | TDP1ATMMAPTUSP10USP7 | |
| SCHEMBL590089 | 0.82 | TDP1 (0.56) | TDP1ATMMAPTTTRALDH1A1 | |
| SCHEMBL1667732 | 0.82 | TDP1 (0.56) | TDP1ATMMAPTTTRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746307-B | Preparation method of 1-nitro-2-ethyl-4-fluorobenzene | 韶远科技（上海)有限公司 | 2021-07-06 | — | — | CN | claimed |
| WO-2021082752-A1 | PREPARATION METHOD FOR 1-NITRO-2-ETHYL-4-FLUOROBENZENE | 韶远科技（上海)有限公司 | 2021-05-06 | — | — | WO | claimed |
| CN-110746307-A | Preparation method of 1-nitro-2-ethyl-4-fluorobenzene | 韶远科技（上海)有限公司 | 2020-02-04 | — | — | CN | claimed |
| CN-117550981-B | Preparation method of 2-amino-5-fluoro acetophenone | 成都工业学院 | 2024-03-15 | — | — | CN | disclosed |
| CN-117550981-A | Preparation method of 2-amino-5-fluoro acetophenone | 成都工业学院 | 2024-02-13 | — | — | CN | disclosed |
| WO-2022216098-A1 | NOVEL LRRK2 INHIBITOR | 주식회사 스탠다임 | 2022-10-13 | — | — | WO | disclosed |
| CN-110746307-B | Preparation method of 1-nitro-2-ethyl-4-fluorobenzene | 韶远科技（上海)有限公司 | 2021-07-06 | — | — | CN | disclosed |
| CN-110746307-B | Preparation method of 1-nitro-2-ethyl-4-fluorobenzene | 韶远科技（上海)有限公司 | 2021-07-06 | — | — | CN | disclosed |
| WO-2021082752-A1 | PREPARATION METHOD FOR 1-NITRO-2-ETHYL-4-FLUOROBENZENE | 韶远科技（上海)有限公司 | 2021-05-06 | — | — | WO | disclosed |
| WO-2021082752-A1 | PREPARATION METHOD FOR 1-NITRO-2-ETHYL-4-FLUOROBENZENE | 韶远科技（上海)有限公司 | 2021-05-06 | — | — | WO | disclosed |
| CN-110746307-A | Preparation method of 1-nitro-2-ethyl-4-fluorobenzene | 韶远科技（上海)有限公司 | 2020-02-04 | — | — | CN | disclosed |
| WO-2005035520-A1 | SUBSTITUTED ISOQUINOLINONES | PORTOLA PHARMACEUTICALS, INC. (US) | 2005-04-21 | — | — | WO | disclosed |
| EP-0442655-B1 | Benzisoxazole derivatives | ZENECA LTD (GB) | 1996-01-17 | — | — | EP | disclosed |
| US-5176737-A | BENZISOXAZOLE COMPOUNDS USEFUL AS HERBICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-01-05 | — | — | US | disclosed |
| EP-0442655-A2 | Benzisoxazole derivatives | ZENECA LIMITED (GB) | 1991-08-21 | — | — | EP | disclosed |
| US-4528025-A | Herbicidally active quinoline or quinoxaline acetophenone oxime derivatives | PPG INDUSTRIES, INC. (US) | 1985-07-09 | — | — | US | disclosed |
| US-4456466-A | Herbicidally active benzoxazolyl acetophenone oxime derivatives | PPG INDUSTRIES, INC. (US) | 1984-06-26 | — | — | US | disclosed |
| US-4440930-A | Herbicidally active quinoline or quinoxaline acetophenone oxime derivatives | PPG INDUSTRIES, INC. (US) | 1984-04-03 | — | — | US | disclosed |
| US-4053470-A | BACTERICIDES, ANTIBIOTICS | PARKE, DAVIS & COMPANY (US) | 1977-10-11 | — | — | US | disclosed |
| US-3954734-A | PENICILLIN AND CEPHALOSPORIN TYPE | PARKE, DAVIS & COMPANY | 1976-05-04 | — | — | US | disclosed |