⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25680268 | 0.77 | ESR1 (0.48) | — | |
| SCHEMBL25680267 | 0.77 | ESR1 (0.48) | — | |
| SCHEMBL30600022 | 0.77 | CES1 (0.44) | — | |
| SCHEMBL5773512 | 0.77 | CES1 (0.44) | — | |
| SCHEMBL16453535 | 0.77 | CES1 (0.44) | — | |
| SCHEMBL16933865 | 0.77 | ESR1 (0.48) | — | |
| SCHEMBL7639343 | 0.77 | ESR1 (0.48) | — | |
| SCHEMBL28830738 | 0.77 | ESR1 (0.48) | — | |
| SCHEMBL16933810 | 0.77 | CES1 (0.44) | — | |
| Benzophenone SCHEMBL27517632 | 0.75 | ALDH1A1 (0.74) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10071984-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RESEARCH, INC. (US) | 2018-09-11 | — | — | US | claimed |
| US-9714230-B2 | Histone demethylase inhibitors | Celgene Quantical Research, Inc. (US) | 2017-07-25 | — | — | US | claimed |
| US-9676770-B2 | Histone demethylase inhibitors | CELGENE QUANTICEL RESEARCH, INC. (US) | 2017-06-13 | — | — | US | claimed |
| EP-2710003-A1 | FUSED BICYCLIC KINASE INHIBITORS | OSI Pharmaceuticals, LLC (US) | 2014-03-26 | — | — | EP | claimed |
| WO-2012158658-A1 | FUSED BICYCLIC KINASE INHIBITORS | OSI Pharmaceuticals, LLC (US) | 2012-11-22 | — | — | WO | claimed |
| EP-0409368-B1 | SUBSTITUTED ALFA PYRIMIDINYLOXY CARBOXYLIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS AN AGENT WITH HERBICIDAL, FUNGICIDAL AND PLANTGROWTH REGULATING ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-11-11 | — | — | EP | claimed |
| US-4243405-A | HYDROXYALKYLTRIAZOLES AND DERIVATIVES, PLANT GROWTH REGULATORS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-01-06 | — | — | US | claimed |
| EP-0001682-A2 | Heterocyclic compounds and their use as pesticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-05-02 | — | — | EP | claimed |
| EP-3154958-B1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES INC (US) | 2020-10-07 | — | — | EP | disclosed |
| US-10092563-B2 | Phosphatidylinositol 3-kinase inhibitors | GILEAD SCIENCES, INC. (US) | 2018-10-09 | — | — | US | disclosed |
| EP-3154958-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | Gilead Sciences, Inc. (US) | 2017-04-19 | — | — | EP | disclosed |
| US-20150361054-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES, INC. | 2015-12-17 | — | — | US | disclosed |
| WO-2015191752-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2015-12-17 | — | — | WO | disclosed |
| CN-104147011-A | Uses of pyridine-diketone serving as PDE4 inhibitor for treating eye diseases | ASTRAZENECA AB | 2014-11-19 | — | — | CN | disclosed |
| US-4605747-A | FUNGICIDES; PLANT GROWTH REGULATORS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-08-12 | — | — | US | disclosed |
| EP-0092352-A1 | 9-Substituted carbacyclins | THE UPJOHN COMPANY (US) | 1983-10-26 | — | — | EP | disclosed |
| EP-0089769-A1 | 9-Substituted carbacyclin analogues | THE UPJOHN COMPANY (US) | 1983-09-28 | — | — | EP | disclosed |
| EP-0086611-A1 | 9-Substituted carbacyclin analogues | THE UPJOHN COMPANY (US) | 1983-08-24 | — | — | EP | disclosed |
| US-4243405-A | HYDROXYALKYLTRIAZOLES AND DERIVATIVES, PLANT GROWTH REGULATORS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-01-06 | — | — | US | disclosed |
| EP-0001682-A2 | Heterocyclic compounds and their use as pesticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-05-02 | — | — | EP | disclosed |