⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597756 | 0.88 | TSHR (0.44) | — | |
| SCHEMBL11616978 | 0.88 | TSHR (0.44) | — | |
| SCHEMBL8511451 | 0.88 | TSHR (0.44) | — | |
| SCHEMBL10863528 | 0.85 | TSHR (0.36) | — | |
| SCHEMBL6193500 | 0.80 | — | — | |
| SCHEMBL164254 | 0.77 | — | — | |
| SCHEMBL11189521 | 0.75 | — | — | |
| SCHEMBL27364217 | 0.71 | OPRM1 (0.32) | — | |
| SCHEMBL8380909 | 0.71 | TRPM8 (0.32) | — | |
| SCHEMBL6564447 | 0.69 | TSHR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 395 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174116-B1 | POLYMERIZATION CATALYST | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1992-04-29 | — | — | EP | claimed |
| US-4618660-A | ORGANOMAGNESIUM COMPOUND REACTED WITH EIRCONIUM COMPOUND HALOGENAT OR, AND TITANIUM COMPOUND; COCATALYST WITH ORGANOALUMINUM COMPOUND | EXXON RESEARCH & ENGINEERING CO. (US) | 1986-10-21 | — | — | US | claimed |
| EP-0177189-A1 | Polymerization catalyst | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1986-04-09 | — | — | EP | claimed |
| US-4578373-A | Polymerization catalyst system | EXXON RESEARCH & ENGINEERING CO. (US) | 1986-03-25 | — | — | US | claimed |
| EP-0174116-A2 | Polymerization catalyst | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1986-03-12 | — | — | EP | claimed |
| US-4562170-A | Polymerization catalyst | EXXON RESEARCH & ENGINEERING CO. (US) | 1985-12-31 | — | — | US | claimed |
| US-4554265-A | POLYOLEFINS HAVING BROAD MOLECULAR WEIGHT DISTRIBUTION | EXXON RESEARCH & ENGINEERING CO. (US) | 1985-11-19 | — | — | US | claimed |
| US-12617883-B2 | Compositions with multimodal ethylene-based polymers having improved toughness at low temperatures | DOW GLOBAL TECHNOLOGIES LLC (US) | 2026-05-05 | — | — | US | disclosed |
| US-12522721-B2 | Polyethylene compositions, films, and articles | DOW GLOBAL TECHNOLOGIES LLC (US) | 2026-01-13 | — | — | US | disclosed |
| US-12448504-B2 | Ziegler-Natta catalyzed polyethylene resins and films incorporating same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2025-10-21 | — | — | US | disclosed |
| US-12440823-B2 | Polymer-based film with balanced properties | DOW GLOBAL TECHNOLOGIES LLC (US) | 2025-10-14 | — | — | US | disclosed |
| US-12441873-B2 | Polymer formulations and irrigation tubing including polymer formulations | DOW GLOBAL TECHNOLOGIES LLC (US) | 2025-10-14 | — | — | US | disclosed |
| EP-3160739-B1 | ETHYLENE-BASED POLYMER COMPOSITION FOR FILMS WITH IMPROVED TOUGHNESS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2025-08-06 | — | — | EP | disclosed |
| US-4246383-A | Process for polymerizing olefins in the presence of a catalyst prepared from an organomagnesium component which does not reduce TiCl4 | THE DOW CHEMICAL COMPANY (US) | 1981-01-20 | — | — | US | disclosed |
| US-4244838-A | High efficiency catalyst for polymerizing olefins | THE DOW CHEMICAL COMPANY (US) | 1981-01-13 | — | — | US | disclosed |
| US-4243785-A | COORDINATION CATALYST HAVING AN ANHYDROUS DIVALENT NICKEL COMPOUND COMPONENT; MOLECULAR WEIGHT CONTROL | THE DOW CHEMICAL COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
| US-4238355-A | A TITANIUM COMPOUND, A ZINC COMPOUND, AN ORGANOMAGNESIUM COMPOUND, AND A HALIDE SOURCE | THE DOW CHEMICAL COMPANY (US) | 1980-12-09 | — | — | US | disclosed |
| US-4224186-A | High efficiency catalyst for polymerizing olefins | THE DOW CHEMICAL COMPANY (US) | 1980-09-23 | — | — | US | disclosed |
| US-4204050-A | HYDROCARBYL TITANIUM HALIDE, VHROMIUM OXIDE, ORGANOALUMINUM COMPOUND, AND A SUPPORT | THE DOW CHEMICAL COMPANY (US) | 1980-05-20 | — | — | US | disclosed |
| US-4198315-A | CONTAINING TITANIUM, ANHYDROUS NICKEL, ORGANOMAGNESIUM AND HALIDE COMPONENTS | THE DOW CHEMICAL COMPANY (US) | 1980-04-15 | — | — | US | disclosed |