Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.41 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2841675 | 0.83 | EGLN3 (0.61) | EGLN3SMN1; SMN2ASAH1LMNAKDM4E | |
| SCHEMBL10469109 | 0.82 | EGLN3 (0.52) | LTA4HEGLN3SMN1; SMN2LMNAALOX15 | |
| SCHEMBL2867039 | 0.79 | EGLN3 (0.62) | EGLN3SMN1; SMN2ASAH1LMNAKDM4E | |
| SCHEMBL10469393 | 0.78 | TBXAS1 (0.48) | LTA4HEGLN3SMN1; SMN2LMNAKDM4E | |
| SCHEMBL10645076 | 0.78 | LTA4H (0.44) | LTA4HEGLN3SMN1; SMN2LMNAKDM4E | |
| SCHEMBL10467879 | 0.77 | TNF (0.53) | LTA4H | |
| SCHEMBL559450 | 0.76 | LTA4H (0.49) | LTA4HSMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL7105950 | 0.76 | LTA4H (0.51) | LTA4HEGLN3SMN1; SMN2LMNAKDM4E | |
| SCHEMBL5748676 | 0.76 | LTA4H (0.51) | LTA4HSMN1; SMN2LMNAKDM4EMAPT | |
| SCHEMBL4647692 | 0.76 | LTA4H (0.45) | LTA4HEGLN3SMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957085-A2 | MACROLIDES AS ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES, LTD. (IN) | 2008-08-20 | — | — | EP | claimed |
| WO-2007054904-A2 | MACROLIDES AS ANTI-INFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-05-18 | — | — | WO | claimed |