SCHEMBL4647729

SCHEMBL4647729

CC(=O)Oc1c(Br)cc(Br)cc1Br

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.50
PREP P48147 3/20 0.41
CFD P00746 2/20 0.41
ALOX15 P16050 2/20 0.40
CA2 P00918 1/20 0.40
ALOX12 P18054 1/20 0.40
CELA1 Q9UNI1 2/20 0.40
KDR P35968 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
BACE1 P56817 1/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
PIK3CG P48736 1/20 0.38
HTT P42858 2/20 0.38
KDM4E B2RXH2 1/20 0.38
TP53 P04637 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18871611 0.90 HSD17B10 (0.46) HSD17B10PREPCFDALOX15CA2
SCHEMBL6936490 0.86 PREP (0.46) HSD17B10PREPCFDCA2CELA1
SCHEMBL4643215 0.86 HSD17B10 (0.43) HSD17B10PREPCFDALOX15CA2
SCHEMBL4318333 0.85 HSD17B10 (0.69) HSD17B10PREPCFDCELA1KDR
SCHEMBL7827341 0.84 PREP (0.48) HSD17B10PREPCFDCA2CELA1
SCHEMBL14430071 0.84 KDM4E (0.44) HSD17B10PREPCFDCA2CELA1
SCHEMBL13864993 0.84 BACE1 (0.50) HSD17B10PREPCA2MEN1KMT2A
SCHEMBL4641645 0.83 ERN1 (0.50) HSD17B10PREPCFDMEN1KMT2A
SCHEMBL9863397 0.83 TPMT (0.42) HSD17B10PREPCA2MEN1KMT2A
SCHEMBL23855075 0.81 HSD17B10 (0.48) HSD17B10ALOX15CA2ALOX12MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed