Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9863177 | 0.89 | HTT (0.42) | TPMTCA5AHTTTSHRAPOBEC3A | |
| SCHEMBL18281058 | 0.86 | TPMT (0.58) | TPMTCA5AHTTTSHRAPOBEC3A | |
| SCHEMBL4934294 | 0.84 | TSHR (0.59) | TPMTHTTTSHRAPOBEC3AAPOBEC3G | |
| SCHEMBL18289199 | 0.84 | TPMT (0.40) | TPMTHTTTSHRAPOBEC3AAPOBEC3G | |
| SCHEMBL4647729 | 0.83 | HSD17B10 (0.50) | HTTTSHRPREPTOP1ABCB11 | |
| SCHEMBL6936490 | 0.83 | PREP (0.46) | TPMTHTTPREPTOP1ABCB11 | |
| SCHEMBL13864993 | 0.81 | BACE1 (0.50) | TPMTLMNAPREPABCB11CA2 | |
| SCHEMBL7827341 | 0.81 | PREP (0.48) | TPMTCA5AHTTPREPTOP1 | |
| SCHEMBL14430071 | 0.81 | KDM4E (0.44) | HTTLMNAPREPTOP1CA2 | |
| SCHEMBL8675250 | 0.77 | KDM4E (0.49) | CA5AHTTTSHRLMNAPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5072025-A | Process for the production of 3,5-disubstituted-4-acetoxystyrene | HOECHST CELANESE CORPORATION (US) | 1991-12-10 | — | — | US | disclosed |
| US-4965400-A | Preparation of 3,5-disubstituted-4-acetoxystyrene | CLARIANT AG (CH) | 1990-10-23 | — | — | US | disclosed |
| US-4933495-A | Process for the production of 3-mono or 3,5 dihalogenated 4-acetoxystyrene, its polymerization, and hydrolysis | HOECHST CELANESE CORPORATION (US) | 1990-06-12 | — | — | US | disclosed |
| US-4927956-A | 3,5-disubstituted-4-acetoxystyrene and process for its production | HOECHST CELANESE CORPORATION (US) | 1990-05-22 | — | — | US | disclosed |
| EP-0356070-A1 | Synthesis of 4-acetoxystyrene oxide and related compounds | HOECHST CELANESE CORPORATION (US) | 1990-02-28 | — | — | EP | disclosed |
| EP-0353339-A2 | A process for the production of poly(3-mono or 3,5-disubstituted-4-Acetoxystryrenes), their copolymers and hydrolysis thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-02-07 | — | — | EP | disclosed |
| US-4868257-A | Process for the production of 3-mono or 3,5 disubstituted-4-acetoxystyrene, its polymerization | HOECHST CELANESE CORPORATION (US) | 1989-09-19 | — | — | US | disclosed |
| US-4868256-A | Process for the production of 3-mono or 3,5-disubstituted-4-acetoxystyrene its polymerization, and hydrolysis | HOECHST CELANESE (US) | 1989-09-19 | — | — | US | disclosed |
| EP-0307751-A2 | 3-mono- and 3,5-disubstituted-4-acetoxy and -4-hydroxystyrenes and process for their production | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-22 | — | — | EP | disclosed |