SCHEMBL13864993

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7225909	0.89	MAPT (0.47)	BACE1ALOX5LMNACYP3A4MAPT
	SCHEMBL6936490	0.84	PREP (0.46)	BACE1MAPTKDM4EMEN1TP53
	SCHEMBL4647729	0.84	HSD17B10 (0.50)	BACE1CYP3A4MAPTKDM4EMEN1
	SCHEMBL7827341	0.83	PREP (0.48)	BACE1ALOX5CYP3A4MAPTKDM4E
	SCHEMBL14430071	0.83	KDM4E (0.44)	BACE1LMNAMAPTKDM4EMEN1
	SCHEMBL7114628	0.83	CYP3A4 (0.47)	BACE1ALOX5LMNACYP3A4MAPT
	SCHEMBL9863397	0.81	TPMT (0.42)	BACE1LMNAMAPTKDM4EMEN1
	SCHEMBL7112160	0.80	BACE1 (0.52)	BACE1LMNACYP3A4MAPTKDM4E
	SCHEMBL18281058	0.79	TPMT (0.58)	BACE1LMNAKDM4EMEN1TTR
	SCHEMBL2010436	0.78	LMNA (0.59)	BACE1LMNACYP3A4MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.