SCHEMBL464815

SCHEMBL464815

C=CC(=O)OCCC[SiH2]O[Si](C)(C)C

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.55
ALDH1A1 P00352 4/20 0.55
CYP3A4 P08684 2/20 0.55
HPGD P15428 1/20 0.55
TP53 P04637 3/20 0.46
HIF1A Q16665 3/20 0.46
HSD17B10 Q99714 1/20 0.46
THRB P10828 2/20 0.39
ATM Q13315 1/20 0.36
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HCAR2 Q8TDS4 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL432362 0.91 TSHR (0.46) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL10114987 0.87 TSHR (0.49) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL10114829 0.85 TSHR (0.47) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL332462 0.85 TSHR (0.50) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL20364753 0.84 ACHE (0.45) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL28137913 0.82 TSHR (0.47) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL336349 0.82 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL7033274 0.82 TSHR (0.35) TSHRALDH1A1CYP3A4HPGDATM
SCHEMBL7878196 0.81 ATM (0.43) TSHRALDH1A1CYP3A4HPGDATM
SCHEMBL30875100 0.81 TSHR (0.43) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112538302-B Bionic fluorine-free coating for petroleum pipeline and preparation method thereof 吉林大学 2021-12-28 CN claimed
CN-112538302-A Bionic fluorine-free coating for petroleum pipeline and preparation method thereof 吉林大学 2021-03-23 CN claimed
EP-3368086-A1 SKIN ADHESIVES, ANTIMICROBIAL COMPOSITIONS, ARTICLES, AND METHODS FOR THE USE THEREOF Dermalink Technologies, Inc. (US) 2018-09-05 EP claimed
WO-2017075320-A1 SKIN ADHESIVES, ANTIMICROBIAL COMPOSITIONS, ARTICLES, AND METHODS FOR THE USE THEREOF DERMALINK TECHNOLOGIES, INC. (US) 2017-05-04 WO claimed
US-20180338945-A1 SKIN ADHESIVES, ANTIMICROBIAL COMPOSITIONS, ARTICLES, AND METHODS FOR THE USE THEREOF DERMALINK TECHNOLOGIES, INC. 2018-11-29 US disclosed
EP-3368086-A1 SKIN ADHESIVES, ANTIMICROBIAL COMPOSITIONS, ARTICLES, AND METHODS FOR THE USE THEREOF Dermalink Technologies, Inc. (US) 2018-09-05 EP disclosed
WO-2017075320-A1 SKIN ADHESIVES, ANTIMICROBIAL COMPOSITIONS, ARTICLES, AND METHODS FOR THE USE THEREOF DERMALINK TECHNOLOGIES, INC. (US) 2017-05-04 WO disclosed
CN-104602886-B There are the preparation method of the copolymer products formed containing organosilicon of hydrophilic surface and the silicone hydrogels contact lenses with hydrophilic surface HOYA株式会社 2017-03-15 CN disclosed
US-9482950-B2 Curable composition for imprints, pattern-forming method and pattern FUJIFILM CORPORATION (JP) 2016-11-01 US disclosed
CN-104602886-A Method for fabricating silicone-containing copolymer molded article having hydrophilic surface and silicone hydrogel contact lens having hydrophilic surface HOYA CORP 2015-05-06 CN disclosed
US-20140050900-A1 CURABLE COMPOSITION FOR IMPRINTS, PATTERN-FORMING METHOD AND PATTERN FUJIFILM CORPORATION (JP) 2014-02-20 US disclosed
EP-1599559-B1 AMINE ORGANOBORANE COMPLEX INITIATED POLYMERIZABLE COMPOSITIONS CONTAINING SILOXANE POLYMERIZABLE COMPONENTS DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-30 EP disclosed
WO-2003097711-A1 POLYMER HAVING CHARGED UNITS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2003-11-27 WO disclosed
US-6586156-B2 A chemically amplified (CA) photoresist system wherein a terpolymer containing ketal/phenolic/silicon based sidechains is provided. Among other things, the terpolymers provide for improved bake technologies. In another aspect a process for INTERNATIONAL BUSINESS MACHINES CORPORATION 2003-07-01 US disclosed
US-20030049561-A1 Etch improved resist systems containing acrylate (or methacrylate) silane monomers INTERNATIONAL BUSINESS MACHINES CORPORATION 2003-03-13 US disclosed
EP-1192194-A1 PROCESS FOR THE MANUFACTURE OF MOLDINGS Novartis AG (CH) 2002-04-03 EP disclosed
WO-2000078830-A1 PROCESS FOR THE MANUFACTURE OF MOLDINGS NOVARTIS AG (CH) 2000-12-28 WO disclosed
EP-0819141-A1 CELL GROWTH SUBSTRATE POLYMER Novartis AG (CH) 1998-01-21 EP disclosed
WO-1996031548-A1 CELL GROWTH SUBSTRATE POLYMER NOVARTIS AG (CH) 1996-10-10 WO disclosed
EP-0294515-A2 Contact lens material Menicon Co., Ltd. (JP) 1988-12-14 EP disclosed