Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18068880 | 0.82 | ALDH1A1 (0.32) | TSHRALDH1A1CYP3A4 | |
| SCHEMBL464815 | 0.82 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL4115638 | 0.77 | TSHR (0.39) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL284885 | 0.75 | TSHR (0.50) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL1799910 | 0.75 | TSHR (0.44) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL20742028 | 0.75 | CHRM2 (0.38) | TSHRATM | |
| SCHEMBL235402 | 0.75 | TSHR (0.36) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL432362 | 0.75 | TSHR (0.46) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL10616185 | 0.74 | — | — | |
| SCHEMBL7878196 | 0.74 | ATM (0.43) | TSHRHPGDALDH1A1CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1287060-A1 | SURFACE TREATMENT OF MEDICAL DEVICE | BAUSCH & LOMB INCORPORATED (US) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001094454-A1 | SURFACE TREATMENT OF MEDICAL DEVICE | BAUSCH & LOMB INCORPORATED (US) | 2001-12-13 | — | — | WO | disclosed |