Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4645874 | 0.86 | ALDH1A1 (0.57) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| SCHEMBL4644760 | 0.82 | ALDH1A1 (0.54) | ALDH1A1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL4648924 | 0.82 | ALDH1A1 (0.58) | ALDH1A1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL4645027 | 0.82 | MMP1 (0.61) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| SCHEMBL4648316 | 0.82 | MMP1 (0.61) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| SCHEMBL4648510 | 0.81 | ALDH1A1 (0.66) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| SCHEMBL4646849 | 0.81 | MMP1 (0.68) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| SCHEMBL7872762 | 0.80 | ALDH1A1 (0.68) | ALDH1A1MAPTLMNATHRBLPAR1 | |
| SCHEMBL4649121 | 0.80 | ALDH1A1 (0.51) | ALDH1A1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL4647932 | 0.80 | MAPT (0.54) | ALDH1A1NPC1RAB9AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957459-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063702-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |