SCHEMBL464824

SCHEMBL464824

C[SiH2]O[Si](OC(C)=O)(OC(C)=O)OC(C)=O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49515 0.76 ALDH1A1 (0.44) ALDH1A1TSHR
SCHEMBL11578060 0.75
SCHEMBL464842 0.73 ALDH1A1 (0.33) ALDH1A1
SCHEMBL9628836 0.72 ALDH1A1 (0.31) ALDH1A1
SCHEMBL9664185 0.71 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL487271 0.69 ALDH1A1 (0.44) ALDH1A1TSHR
SCHEMBL487443 0.69 ALDH1A1 (0.44) ALDH1A1TSHR
SCHEMBL3912403 0.69 ALDH1A1 (0.44) ALDH1A1TSHR
SCHEMBL3912674 0.67 ALDH1A1 (0.42) ALDH1A1TSHR
SCHEMBL8853295 0.67 ALDH1A1 (0.35) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2490663-B1 SILICONE COMPOSITIONS COMPRISING A SWOLLEN SILICONE GEL DOW CORNING (US) 2017-09-20 EP disclosed
US-9624334-B2 Hydrophilically-modified silicone compositions DOW CORNING CORPORATION (US) 2017-04-18 US disclosed
US-9574109-B2 Surface-modified hydrogels and hydrogel microparticles DOW CORNING CORPORATION (US) 2017-02-21 US disclosed
US-9243113-B2 Silicone compositions comprising a swollen silicone gel DOW CORNING CORPORATION (US) 2016-01-26 US disclosed
EP-2536786-B1 SURFACE-MODIFIED HYDROGELS AND HYDROGEL MICROPARTICLES DOW CORNING (US) 2015-12-30 EP disclosed
EP-2491065-B1 HYDROPHILICALLY-MODIFIED SILICONE COMPOSITIONS DOW CORNING (US) 2014-11-26 EP disclosed
US-8865266-B2 Method of coating a porous substrate DOW CORNING CORPORATION (US) 2014-10-21 US disclosed
EP-2675538-A1 METHOD OF COATING A POROUS SUBSTRATE Dow Corning Corporation (US) 2013-12-25 EP disclosed
US-20130316087-A1 METHOD OF COATING A POROUS SUBSTRATE DOW CORNING CORPORATION (MI) 2013-11-28 US disclosed
EP-2536766-A1 SILOXANE SURFACE-MODIFIED HYDROGEL AND HYDROGEL MICROPARTICLE COMPOSITIONS Dow Corning Corporation (US) 2012-12-26 EP disclosed
US-20040210015-A1 AMINE ORGANOBORANE COMPLEX INITIATED POLYMERIZABLE COMPOSITIONS CONTAINING SILOXANE POLYMERIZABLE COMPONENTS SONNENSCHEIN MARK F (US) 2004-10-21 US disclosed
WO-2004078871-A1 AMINE ORGANOBORANE COMPLEX INITIATED POLYMERIZABLE COMPOSITIONS CONTAINING SILOXANE POLYMERIZABLE COMPONENTS DOW GLOBAL TECHNOLOGIES INC. (US) 2004-09-16 WO disclosed
US-6777512-B1 MONOMERS, OLIGOMERS OR POLYMERS HAVING A SILOXANE BACKBONE CONTAINS ACRYLATE FUNCTIONAL MOIETIES DOW GLOBAL TECHNOLOGIES INC. 2004-08-17 US disclosed
WO-1998017277-A1 AMIDINE COMPOUNDS FOR USE IN SYSTEMIC TREATING ECTO AND/OR ENDO PARASITIC DISEASES VIRBAC S.A. (FR) 1998-04-30 WO disclosed
EP-0836851-A1 Amidine compounds for use in treating ecto or endo parasitic diseases and systemic parasite control compositions VIRBAC S.A. (FR) 1998-04-22 EP disclosed
US-5728719-A Systemic control of parasites VIRBAC, INC. (US) 1998-03-17 US disclosed
EP-0549441-B1 Juvenile hormone agents for systemically treating ectoparasites VIRBAC INC (US) 1997-08-06 EP disclosed
US-5439924-A Using an antifertility agent VIRBAC, INC. (US) 1995-08-08 US disclosed
EP-0549441-A1 Juvenile hormone agents for systemically treating ectoparasites Virbac, Inc. (US) 1993-06-30 EP disclosed
US-4138387-A Poly(olefinic monomer) filled-poly(organosiloxane) compositions GENERAL ELECTRIC COMPANY (US) 1979-02-06 US disclosed