⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28049267 | 0.76 | — | — | |
| SCHEMBL7165758 | 0.72 | — | — | |
| SCHEMBL28885993 | 0.71 | — | — | |
| SCHEMBL11215480 | 0.67 | — | — | |
| SCHEMBL8912583 | 0.67 | — | — | |
| SCHEMBL28938216 | 0.65 | — | — | |
| SCHEMBL7212460 | 0.63 | GLS (0.36) | — | |
| SCHEMBL15116531 | 0.63 | GLS (0.36) | — | |
| SCHEMBL3116445 | 0.62 | — | — | |
| SCHEMBL10875348 | 0.62 | FFAR3 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2490663-B1 | SILICONE COMPOSITIONS COMPRISING A SWOLLEN SILICONE GEL | DOW CORNING (US) | 2017-09-20 | — | — | EP | disclosed |
| US-9624334-B2 | Hydrophilically-modified silicone compositions | DOW CORNING CORPORATION (US) | 2017-04-18 | — | — | US | disclosed |
| US-9574109-B2 | Surface-modified hydrogels and hydrogel microparticles | DOW CORNING CORPORATION (US) | 2017-02-21 | — | — | US | disclosed |
| US-9243113-B2 | Silicone compositions comprising a swollen silicone gel | DOW CORNING CORPORATION (US) | 2016-01-26 | — | — | US | disclosed |
| EP-2536786-B1 | SURFACE-MODIFIED HYDROGELS AND HYDROGEL MICROPARTICLES | DOW CORNING (US) | 2015-12-30 | — | — | EP | disclosed |
| EP-2491065-B1 | HYDROPHILICALLY-MODIFIED SILICONE COMPOSITIONS | DOW CORNING (US) | 2014-11-26 | — | — | EP | disclosed |
| US-8865266-B2 | Method of coating a porous substrate | DOW CORNING CORPORATION (US) | 2014-10-21 | — | — | US | disclosed |
| EP-2675538-A1 | METHOD OF COATING A POROUS SUBSTRATE | Dow Corning Corporation (US) | 2013-12-25 | — | — | EP | disclosed |
| US-20130316087-A1 | METHOD OF COATING A POROUS SUBSTRATE | DOW CORNING CORPORATION (MI) | 2013-11-28 | — | — | US | disclosed |
| EP-2536766-A1 | SILOXANE SURFACE-MODIFIED HYDROGEL AND HYDROGEL MICROPARTICLE COMPOSITIONS | Dow Corning Corporation (US) | 2012-12-26 | — | — | EP | disclosed |
| WO-2011109174-A1 | SURFACE -MODIFIED HYDROGELS AND HYDROGEL MICROPARTICLES | DOW CORNING CORPORATION (US) | 2011-09-09 | — | — | WO | disclosed |
| WO-2011103291-A1 | SILOXANE SURFACE-MODIFIED HYDROGEL AND HYDROGEL MICROPARTICLE COMPOSITIONS | DOW CORNING CORPORATION (US) | 2011-08-25 | — | — | WO | disclosed |
| WO-2011049896-A2 | SILICONE COMPOSITIONS COMPRISING A SWOLLEN SILICONE GEL | DOW CORNING CORPORATION (US) | 2011-04-28 | — | — | WO | disclosed |
| US-7157399-B2 | Amine organoborane complex initiated polymerizable compositions containing siloxane polymerizable components | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-01-02 | — | — | US | disclosed |
| US-6949603-B2 | Amine organoborane complex initiated polymerizable compositions containing siloxane polymerizable components | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-09-27 | — | — | US | disclosed |
| US-20040242812-A1 | Amine organoborane complex initiated polymerizable compositions containing siloxane polymerizable components | DOW GLOBAL TECHNOLOGIES INC. | 2004-12-02 | — | — | US | disclosed |
| US-6825298-B2 | CATALYTIC FREE RADICAL ADDITION POLYMERIZATION OF OLEFINICALLY UNSATURATED MONOMOERS; CURING ADHESIVES; BONDING STRENGTH, HEAT RESISTANCE | DOW GLOBAL TECHNOLOGIES INC. | 2004-11-30 | — | — | US | disclosed |
| US-20040220363-A1 | Amine organoborane complex initiated polymerizable compositions containing siloxane polymerizable components | DOW GLOBAL TECHNOLOGIES LLC | 2004-11-04 | — | — | US | disclosed |
| US-20040210015-A1 | AMINE ORGANOBORANE COMPLEX INITIATED POLYMERIZABLE COMPOSITIONS CONTAINING SILOXANE POLYMERIZABLE COMPONENTS | SONNENSCHEIN MARK F (US) | 2004-10-21 | — | — | US | disclosed |
| US-6777512-B1 | MONOMERS, OLIGOMERS OR POLYMERS HAVING A SILOXANE BACKBONE CONTAINS ACRYLATE FUNCTIONAL MOIETIES | DOW GLOBAL TECHNOLOGIES INC. | 2004-08-17 | — | — | US | disclosed |