Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.65 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.62 |
| ▸ | PPARG | P37231 | 7/20 | 0.62 |
| ▸ | PPARD | Q03181 | 7/20 | 0.62 |
| ▸ | PPARA | Q07869 | 7/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.62 |
| ▸ | TSHR | P16473 | 4/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.62 |
| ▸ | FABP4 | P15090 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | TLR2 | O60603 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.62 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ESR1 | P03372 | 1/20 | 0.62 |
| ▸ | PDE4A | P27815 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL28409819 | 1.00 | AKR1B1 (0.65) | AKR1B1GPR84PPARGPPARDPPARA | |
| Adipic Acid SCHEMBL52475 | 1.00 | AKR1B1 (0.65) | AKR1B1GPR84PPARGPPARDPPARA | |
| Hexanoate SCHEMBL28254054 | 0.98 | AKR1B1 (0.70) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL26034547 | 0.98 | AKR1B1 (0.62) | AKR1B1GPR84PPARGPPARDPPARA | |
| Adipic Acid SCHEMBL2512259 | 0.98 | AKR1B1 (0.68) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL9007925 | 0.96 | GPR84 (0.64) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL446914 | 0.95 | AKR1B1 (0.65) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL17908712 | 0.95 | AKR1B1 (0.58) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL17909689 | 0.95 | AKR1B1 (0.58) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL380287 | 0.95 | AKR1B1 (0.58) | AKR1B1GPR84PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 508 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118006115-B | Ageing-resistant cable and processing technology thereof | 广东万瑞通电缆实业有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-118006115-A | Ageing-resistant cable and processing technology thereof | 广东万瑞通电缆实业有限公司 | 2024-05-10 | — | — | CN | claimed |
| CN-115975364-A | Toughened polylactic acid/starch multi-component blending material and preparation method thereof | 湖北工业大学 | 2023-04-18 | — | — | CN | claimed |
| CN-115612218-B | High-aging-resistance rubber sheath for cable and preparation method thereof | 瑞安达电缆有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-115772287-A | Low-pressure-change high-temperature-resistant hot oil nitrile rubber compound and preparation method thereof | 宁国市赛科思橡胶有限公司 | 2023-03-10 | — | — | CN | claimed |
| CN-115627018-A | Preparation method of ageing-resistant high-elasticity rubber compound | 江苏创合橡塑有限公司 | 2023-01-20 | — | — | CN | claimed |
| CN-115612218-A | High-aging-resistance rubber sheath for cable and preparation method thereof | 瑞安达电缆有限公司 | 2023-01-17 | — | — | CN | claimed |
| CN-109824988-B | Sealing strip composite material and preparation method thereof | 柳州宏桂汽车零部件有限公司 | 2022-09-06 | — | — | CN | claimed |
| CN-114806037-A | Wear-resistant polyvinyl chloride cable material and preparation method thereof | 江苏益帆高分子材料有限公司 | 2022-07-29 | — | — | CN | claimed |
| CN-114790325-A | Bio-based fully-degradable thin-wall injection molding material and preparation method thereof | 丹阳恒绿新材料有限公司 | 2022-07-26 | — | — | CN | claimed |
| US-9932458-B2 | Rubber composition for flexible coupling | HYUNDAI MOTOR COMPANY (KR) | 2018-04-03 | — | — | US | claimed |
| EP-3112407-A1 | RUBBER COMPOSITION FOR FLEXIBLE COUPLING | Hyundai Motor Company (KR) | 2017-01-04 | — | — | EP | claimed |
| US-20160376415-A1 | RUBBER COMPOSITION FOR FLEXIBLE COUPLING | TSR CO., LTD. (KR) | 2016-12-29 | — | — | US | claimed |
| EP-2153986-B1 | HOUSING COMPRISING RESIN COATED FLANGES AND A DIAPHRAGM COMPRISING A RUBBER COMPOSITION AND A PLASTICIZER | FISHER CONTROLS INT LLC (US) | 2016-12-07 | — | — | EP | claimed |
| US-7786210-B2 | Plasticized poly(hydroxyalkanoic acid) composition | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-08-31 | — | — | US | claimed |
| WO-2009064851-A2 | PLASTICIZED POLY(HYDROXYALKANOIC ACID) COMPOSITION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-05-22 | — | — | WO | claimed |
| US-20090131566-A1 | PLASTICIZED POLY(HYDROXYALKANOIC ACID) COMPOSITION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-05-21 | — | — | US | claimed |
| US-6037025-A | HEAT-RESISTANT AND OIL-RESISTANT REINFORCED POWER STEERING HOSES | TOYODA GOSEI CO., LTD. (JP) | 2000-03-14 | — | — | US | claimed |
| US-5822671-A | Image forming method and apparatus for forming a resin-formed image on a fabric, fiber or other such recording medium | MINOLTA CO., LTD. (JP) | 1998-10-13 | — | — | US | claimed |
| US-5102953-A | Polysiloxaneurethane copolymer and polyvinyl chloride blends | NIPPON POLURETHANE INDUSTRY CO., LTD. (JP) | 1992-04-07 | — | — | US | claimed |