Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.65 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.62 |
| ▸ | PPARG | P37231 | 7/20 | 0.62 |
| ▸ | PPARD | Q03181 | 7/20 | 0.62 |
| ▸ | PPARA | Q07869 | 7/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.62 |
| ▸ | TSHR | P16473 | 4/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.62 |
| ▸ | FABP4 | P15090 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | TLR2 | O60603 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.62 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ESR1 | P03372 | 1/20 | 0.62 |
| ▸ | PDE4A | P27815 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL28409819 | 1.00 | AKR1B1 (0.65) | AKR1B1GPR84PPARGPPARDPPARA | |
| Adipic Acid SCHEMBL464839 | 1.00 | AKR1B1 (0.65) | AKR1B1GPR84PPARGPPARDPPARA | |
| Hexanoate SCHEMBL28254054 | 0.98 | AKR1B1 (0.70) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL26034547 | 0.98 | AKR1B1 (0.62) | AKR1B1GPR84PPARGPPARDPPARA | |
| Adipic Acid SCHEMBL2512259 | 0.98 | AKR1B1 (0.68) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL9007925 | 0.96 | GPR84 (0.64) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL446914 | 0.95 | AKR1B1 (0.65) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL17908712 | 0.95 | AKR1B1 (0.58) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL17909689 | 0.95 | AKR1B1 (0.58) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL380287 | 0.95 | AKR1B1 (0.58) | AKR1B1GPR84PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773937-A4 | PROCESSING AID FOR PVC AND METHOD FOR MANUFACTURING THE SAME | LG CHEMICAL LTD (KR) | 2009-01-14 | — | — | EP | claimed |
| US-20080139713-A1 | A methyl methacrylate copolymer plasticizer or internal lubricant; microemulsification with a ultrahydrophobe, a plasticizer or an internal lubricant, an emulsifier, and an initiator; emulsion copolymerization, spray drying; increased melt speed and processability | LG CHEM, LTD. (KR) | 2008-06-12 | — | — | US | claimed |
| CN-101006129-A | Processing aid for PVC and method for manufacturing the same | LG CHEMICAL LTD (KR) | 2007-07-25 | — | — | CN | claimed |
| EP-1773937-A1 | PROCESSING AID FOR PVC AND METHOD FOR MANUFACTURING THE SAME | LG Chem, Ltd. (KR) | 2007-04-18 | — | — | EP | claimed |
| WO-2006062366-A1 | PROCESSING AID FOR PVC AND METHOD FOR MANUFACTURING THE SAME | LG CHEM, LTD. (KR) | 2006-06-15 | — | — | WO | claimed |
| US-6235400-B1 | Vibration-isolating laminar rubber structure having rubber layers whose composition includes at least one of asphalt, tar and pitch materials | TOKAI RUBBER INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | claimed |
| US-4684054-A | Automatic soldering apparatus and method of using the flux to heat the circuit board | ASAHI CHEMICAL RESEARCH LABORATORY CO., LTD. (JP) | 1987-08-04 | — | — | US | claimed |
| JP-11079433-A | — | — | None | — | — | JP | disclosed |
| JP-6256599-A | — | — | None | — | — | JP | disclosed |
| US-20240110647-A1 | FUEL HOSE | SUMITOMO RIKO COMPANY LIMITED (JP) | 2024-04-04 | — | — | US | disclosed |
| WO-2023187992-A1 | HOSE FOR FUELS | 住友理工株式会社 | 2023-10-05 | — | — | WO | disclosed |
| US-20220131205-A1 | USE OF AN ESTER IN A COOLING COMPOSITION | TOTALENERGIES ONETECH (FR) | 2022-04-28 | — | — | US | disclosed |
| EP-3571244-B1 | FOAMED COMPOSITION | DSM IP ASSETS BV (NL) | 2022-03-16 | — | — | EP | disclosed |
| US-5546108-A | Ink-jet type recorder having an ink carrier and letting ink by combined heat and eletrostatic force | MINOLTA CAMERA KABUSHIKI KAISHA (JP) | 1996-08-13 | — | — | US | disclosed |
| EP-0347246-B1 | Method for manufacturing Lithographic printing plates | FUJI PHOTO FILM CO LTD (JP) | 1995-12-20 | — | — | EP | disclosed |
| JP-H06256599-A | OIL BLEEDING EPDM RUBBER | INOAC CORP | 1994-09-13 | — | — | JP | disclosed |
| US-5002857-A | Method for manufacturing lithographic printing plates | FUJI PHOTO FILM CO., LTD. (JP) | 1991-03-26 | — | — | US | disclosed |
| EP-0347246-A2 | Method for manufacturing Lithographic printing plates | FUJI PHOTO FILM CO., LTD. (JP) | 1989-12-20 | — | — | EP | disclosed |
| US-4390520-A | INDOMETHACIN AND ACRYLIC-VINYL COPOLYMER | NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1983-06-28 | — | — | US | disclosed |
| US-3974080-A | PHOSPHORIC ACID ESTER | UNION CARBIDE CORPORATION (US) | 1976-08-10 | — | — | US | disclosed |