SCHEMBL4648494

SCHEMBL4648494

CC(C)(c1ccc(O)cc1)c1cccc(O)c1.CCC(C)(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 11/20 0.66
ESR2 Q92731 9/20 0.66
CYP3A4 P08684 3/20 0.55
ALDH1A1 P00352 2/20 0.55
AR P10275 1/20 0.52
HPGD P15428 1/20 0.52
TSHR P16473 1/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A4 P31645 1/20 0.52
HTR6 P50406 1/20 0.52
ESRRG P62508 1/20 0.52
SLC6A3 Q01959 1/20 0.52
HSD17B10 Q99714 1/20 0.52
CNR1 P21554 2/20 0.39
CNR2 P34972 2/20 0.39
LMNA P02545 1/20 0.38
TYR P14679 1/20 0.38
RORC P51449 1/20 0.38
KLF10 Q13118 1/20 0.38
SHBG P04278 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6516890 0.92 ESR1 (0.52) ESR1ESR2CYP3A4ALDH1A1AR
SCHEMBL124881 0.88 ESR1 (0.84) ESR1ESR2CYP3A4ALDH1A1AR
SCHEMBL29368890 0.88 ESR1 (0.84) ESR1ESR2CYP3A4ALDH1A1AR
SCHEMBL24167936 0.88 ESR1 (0.84) ESR1ESR2CYP3A4ALDH1A1AR
Bisphenol A SCHEMBL674171 0.86 ESR1 (0.70) ESR1ESR2CYP3A4ALDH1A1AR
SCHEMBL11783483 0.84 ALDH1A1 (0.44) ESR1ESR2CYP3A4ALDH1A1TSHR
SCHEMBL10492973 0.84 ESR1 (0.76) ESR1ESR2CYP3A4ALDH1A1AR
SCHEMBL23905030 0.81 ESR1 (0.63) ESR1ESR2CYP3A4ALDH1A1AR
Phenol SCHEMBL8467840 0.81 ESR1 (0.57) ESR1ESR2CYP3A4ALDH1A1AR
Bisphenol A SCHEMBL11875900 0.80 ESR1 (0.76) ESR1ESR2CYP3A4ALDH1A1AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2655473-B1 METHOD FOR MAKING POLYCARBONATE SABIC GLOBAL TECHNOLOGIES BV (NL) 2016-07-06 EP disclosed
EP-2655473-A1 METHOD FOR MAKING POLYCARBONATE SABIC Innovative Plastics IP B.V. (NL) 2013-10-30 EP disclosed
US-8263729-B2 Method for making polycarbonate SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-09-11 US disclosed
WO-2012085831-A1 METHOD FOR MAKING POLYCARBONATE SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-06-28 WO disclosed
US-20120157639-A1 METHOD FOR MAKING POLYCARBONATE SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-06-21 US disclosed
EP-2007829-A1 THERMOPLASTIC POLYCARBONATE COMPOSITIONS, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF Sabic Innovative Plastics IP B.V. (NL) 2008-12-31 EP disclosed
EP-1973969-A1 THERMOPLASTIC POLYCARBONATE COMPOSITIONS, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF Sabic Innovative Plastics IP B.V. (NL) 2008-10-01 EP disclosed
EP-1957560-A2 POLYCARBONATE USEFUL IN MAKING SOLVENT CAST FILMS General Electric Company (US) 2008-08-20 EP disclosed
EP-1824899-A1 METHOD FOR MAKING POLYCARBONATE General Electric Company (US) 2007-08-29 EP disclosed
WO-2007037952-A1 THERMOPLASTIC POLYCARBONATE COMPOSITIONS, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF GENERAL ELECTRIC COMPANY (US) 2007-04-05 WO disclosed
WO-2007037887-A1 THERMOPLASTIC POLYCARBONATE COMPOSITIONS, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF GENERAL ELECTRIC COMPANY (US) 2007-04-05 WO disclosed
US-20070072960-A1 Thermoplastic polycarbonate compositions, method of manufacture, and method of use thereof GENERAL ELECTRIC COMPANY (US) 2007-03-29 US disclosed
US-20070072961-A1 Thermoplastic polycarbonate compositions, method of manufacture, and method of use thereof GENERAL ELECTRIC COMPANY (US) 2007-03-29 US disclosed
WO-2007032880-A2 POLYCARBONATE USEFUL IN MAKING SOLVENT CAST FILMS GENERAL ELECTRIC COMPANY (US) 2007-03-22 WO disclosed
US-20070057400-A1 Polycarbonate useful in making solvent cast films GENERAL ELECTRIC COMPANY (US) 2007-03-15 US disclosed
US-7189869-B2 Method for making polycarbonate GENERAL ELECTRIC COMPANY (US) 2007-03-13 US disclosed
US-7183371-B2 Method for making polycarbonate GENERAL ELECTRIC COMPANY (US) 2007-02-27 US disclosed
WO-2006049955-A1 METHOD FOR MAKING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2006-05-11 WO disclosed
US-20060094854-A1 METHOD FOR MAKING POLYCARBONATE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2006-05-04 US disclosed
US-20060094856-A1 Method for making polycarbonate SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2006-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060094856-A1 Method for making polycarbonate PIK3CA, HPD, POLI ESR1 419/4885ESR2 1405/4885CYP3A4 749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.