Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL291602 | 0.80 | ALDH1A1 (0.52) | TSHRAPPALDH1A1CA1CA2 | |
| SCHEMBL153943 | 0.76 | TSHR (0.67) | TSHRAPPALDH1A1CA1CA2 | |
| SCHEMBL97582 | 0.76 | CA1 (0.52) | TSHRALDH1A1CA1CA2CYP3A4 | |
| SCHEMBL2720527 | 0.76 | HPGD (0.48) | TSHRAPPALDH1A1HPGDHSD17B10 | |
| SCHEMBL27795222 | 0.76 | CA1 (0.39) | CA1CA2 | |
| SCHEMBL2290799 | 0.74 | HRH3 (0.50) | TSHRAPPCA1CA2CA12 | |
| SCHEMBL2643173 | 0.74 | TSHR (0.43) | TSHRAPPALDH1A1CA1CA2 | |
| SCHEMBL15389539 | 0.74 | APP (0.49) | TSHRAPPALDH1A1CA1CA2 | |
| SCHEMBL21081404 | 0.74 | APP (0.47) | TSHRAPPALDH1A1CA1CA2 | |
| SCHEMBL7049861 | 0.74 | APP (0.47) | TSHRAPPALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963296-A2 | OPTICALLY ACTIVE CARBAMATES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS PHARMACEUTICAL INTERMEDIATES | Egis Gyógyszergyár Nyilvánosan Múködö Részvénytársaság (HU) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007066163-A2 | OPTICALLY ACTIVE CARBAMATES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS PHARMACEUTICAL INTERMEDIATES | Egis Gyógyszergyár Nyilvanosan Mukodo Reszvenytarsasag (HU) | 2007-06-14 | — | — | WO | disclosed |
| CN-1315453-C | Hair treatment composition comprising composite particles of clay and charged organic molecule | UNILEVER PLC (NL) | 2007-05-16 | — | — | CN | disclosed |
| CN-1599591-A | Hair treatment composition comprising composite particles of clay and charged organic molecule | UNILEVER PLC (NL) | 2005-03-23 | — | — | CN | disclosed |