Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2335646 | 0.93 | MEN1 (0.34) | MEN1TSHRKMT2A | |
| SCHEMBL793408 | 0.89 | — | — | |
| SCHEMBL793302 | 0.89 | — | — | |
| SCHEMBL1571074 | 0.83 | MEN1 (0.32) | MEN1TSHRKMT2A | |
| SCHEMBL11040106 | 0.82 | MEN1 (0.31) | MEN1TSHRKMT2A | |
| SCHEMBL2578537 | 0.78 | LMNA (0.36) | TSHR | |
| SCHEMBL794100 | 0.78 | MEN1 (0.34) | MEN1TSHRKMT2A | |
| SCHEMBL793843 | 0.78 | MEN1 (0.34) | MEN1TSHRKMT2A | |
| SCHEMBL2546193 | 0.77 | — | — | |
| SCHEMBL2330617 | 0.77 | MEN1 (0.30) | MEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960389-A2 | COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007036718-A2 | COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2007-04-05 | — | — | WO | disclosed |