Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL794100 | 1.00 | MEN1 (0.34) | MEN1TSHRKMT2A | |
| SCHEMBL1563472 | 0.95 | MEN1 (0.30) | MEN1TSHRKMT2A | |
| SCHEMBL2330617 | 0.95 | MEN1 (0.30) | MEN1TSHRKMT2A | |
| SCHEMBL793408 | 0.89 | — | — | |
| SCHEMBL793302 | 0.89 | — | — | |
| SCHEMBL2335646 | 0.86 | MEN1 (0.34) | MEN1TSHRKMT2A | |
| SCHEMBL5968494 | 0.81 | TSHR (0.35) | MEN1TSHRKMT2A | |
| SCHEMBL6421985 | 0.81 | TSHR (0.35) | MEN1TSHRKMT2A | |
| SCHEMBL5547601 | 0.79 | CYP2D6 (0.35) | MEN1TSHRKMT2A | |
| SCHEMBL3994294 | 0.79 | CYP2D6 (0.35) | MEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035055-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-22 | — | — | WO | disclosed |
| WO-2010091721-A1 | 3 -SUBSTITUTED 1-ARYLSULFONYLPIPERIDINE DERIVATIVES FOR THE TREATMENT OF PAIN | GLAXO GROUP LIMITED (GB) | 2010-08-19 | — | — | WO | disclosed |