Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | GALK1 | P51570 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | LGMN | Q99538 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14983919 | 0.77 | PSMD14 (0.60) | PSMD14MEN1KMT2ANPC1RAB9A | |
| SCHEMBL14983921 | 0.77 | PSMD14 (0.60) | PSMD14MEN1KMT2ANPC1RAB9A | |
| SCHEMBL4648976 | 0.75 | PSMD14 (0.39) | PSMD14MEN1KMT2ALGMNPRKDC | |
| SCHEMBL14973406 | 0.73 | PSMD14 (0.68) | PSMD14MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7284139 | 0.70 | MAPT (0.50) | PSMD14MEN1KMT2ANPC1RAB9A | |
| SCHEMBL14983933 | 0.70 | PSMD14 (0.52) | PSMD14MEN1KMT2ANPC1RAB9A | |
| SCHEMBL14983938 | 0.70 | PSMD14 (0.52) | PSMD14PRKDCTSHRADORA2AADORA1 | |
| SCHEMBL14983941 | 0.70 | ADORA2A (0.53) | PSMD14MEN1KMT2ANPC1RAB9A | |
| SCHEMBL16081777 | 0.70 | PSMD14 (0.52) | PSMD14MEN1KMT2ALGMNPRKDC | |
| SCHEMBL14983934 | 0.70 | PSMD14 (0.52) | PSMD14MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961738-A1 | New compounds with antiglutamatergic properties and uses thereof | Faust Pharmaceuticals (FR) | 2008-08-27 | — | — | EP | disclosed |
| EP-1961738-A1 | New compounds with antiglutamatergic properties and uses thereof | Faust Pharmaceuticals (FR) | 2008-08-27 | — | — | EP | disclosed |
| WO-2008098751-A1 | NEW COMPOUNDS WITH ANTIGLUTAMATERGIC PROPERTIES AND USES THEREOF | FAUST PHARMACEUTICALS (FR) | 2008-08-21 | — | — | WO | disclosed |