Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.36 |
| ▸ | LGMN | Q99538 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4648972 | 1.00 | PSMD14 (0.39) | PSMD14ADORA2AADORA1MAPTKDM4E | |
| SCHEMBL4648755 | 0.75 | PSMD14 (0.49) | PSMD14ADORA2AADORA1MAPTALDH1A1 | |
| SCHEMBL4648731 | 0.74 | KMT2A (0.39) | KDM4EMEN1GAAKMT2ACA1 | |
| SCHEMBL4648727 | 0.74 | KMT2A (0.39) | KDM4EMEN1GAAKMT2ACA1 | |
| SCHEMBL8171243 | 0.72 | NPC1 (0.55) | ADORA2AADORA1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4648045 | 0.72 | PTPRC (0.40) | MAPTKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL4649478 | 0.71 | APAF1 (0.56) | MAPTKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8170729 | 0.71 | APAF1 (0.56) | MAPTKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL4649480 | 0.71 | APAF1 (0.56) | MAPTKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL4648903 | 0.67 | KMT2A (0.39) | KDM4EMEN1GAAKMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961738-A1 | New compounds with antiglutamatergic properties and uses thereof | Faust Pharmaceuticals (FR) | 2008-08-27 | — | — | EP | disclosed |