Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 10/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.40 |
| ▸ | PI4KA | P42356 | 7/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 7/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 7/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 7/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenine SCHEMBL4025869 | 0.87 | PI4KA (0.41) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| Adenine SCHEMBL28115851 | 0.86 | PI4KA (0.40) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| Adenine SCHEMBL3414603 | 0.85 | PI4KA (0.48) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| Adenine SCHEMBL3413247 | 0.85 | PI4KA (0.48) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| Adenine SCHEMBL3416954 | 0.85 | PI4KA (0.48) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| Adenine SCHEMBL8110 | 0.85 | PI4KA (0.48) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| Adenine SCHEMBL1871837 | 0.83 | PI4KA (0.44) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| Adenine SCHEMBL10868999 | 0.83 | PI4KA (0.47) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| Adenine SCHEMBL2895675 | 0.83 | PI4KA (0.47) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| Adenine SCHEMBL7204509 | 0.83 | PI4KA (0.50) | ADORA2AADORA1PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293666-A1 | Antibacterial Agents | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2008-11-27 | — | — | US | disclosed |
| EP-1960518-A2 | ANTIBACTERIAL AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007067559-A2 | ANTIBACTERIAL AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2007-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293666-A1 | Antibacterial Agents | MRPL21, ABCB7, MSR1 | ADORA2A 2428/4885ADORA1 865/4885PI4KA 4490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.