Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 14/20 | 0.59 |
| ▸ | ITGB1 | P05556 | 11/20 | 0.59 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.52 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.52 |
| ▸ | ITGAL | P20701 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 10/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649073 | 1.00 | ITGA4 (0.59) | ITGA4ITGB1ITGB2ICAM1ITGAL | |
| SCHEMBL4648129 | 0.94 | ITGA4 (0.53) | ITGA4ITGB1ITGB2ICAM1ITGAL | |
| SCHEMBL4649378 | 0.93 | ITGB1 (0.52) | ITGA4ITGB1ITGB2ICAM1ITGAL | |
| SCHEMBL4648600 | 0.93 | ITGB1 (0.52) | ITGA4ITGB1ITGB2ICAM1ITGAL | |
| SCHEMBL4649380 | 0.92 | ITGA4 (0.49) | ITGA4ITGB1ITGB2ICAM1ITGAL | |
| SCHEMBL4649382 | 0.92 | ITGA4 (0.49) | ITGA4ITGB1ITGB2ICAM1ITGAL | |
| SCHEMBL4648018 | 0.91 | ITGA4 (0.49) | ITGA4ITGB1ITGB2ICAM1ITGAL | |
| SCHEMBL4648841 | 0.91 | ITGA4 (0.49) | ITGA4ITGB1ITGB2ICAM1ITGAL | |
| SCHEMBL4648806 | 0.91 | ITGB1 (0.49) | ITGA4ITGB1ITGB2ICAM1ITGAL | |
| SCHEMBL4648805 | 0.91 | ITGB1 (0.49) | ITGA4ITGB1ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701933-B1 | NOVEL COMPOUNDS | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-09-03 | — | — | EP | claimed |
| US-20070043113-A1 | Novel compounds | TANABE SEIYAKU CO., LTD. (JP) | 2007-02-22 | — | — | US | claimed |
| EP-1701933-A1 | NOVEL COMPOUNDS | TANABE SEIYAKU CO., LTD. (JP) | 2006-09-20 | — | — | EP | claimed |
| WO-2005061440-A1 | NOVEL COMPOUNDS | TANABE SEIYAKU CO., LTD. (JP) | 2005-07-07 | — | — | WO | claimed |
| EP-1701933-B1 | NOVEL COMPOUNDS | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-09-03 | — | — | EP | disclosed |
| EP-1964040-A2 | COMPUTATIONAL AND/OR CONTROL SYSTEMS RELATED TO INDIVIDUALIZED PHARMACEUTICAL AND NUTRACEUTICAL SELECTION AND PACKAGING | Searete LLC. (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007075378-A2 | CONTROL SYSTEMS FOR INDIVIDUALIZED PHARMACEUTICAL AND NUTRACEUTICAL SELECTION AND PACKAGING | SEARETE LLC (US) | 2007-07-05 | — | — | WO | disclosed |
| US-20070043113-A1 | Novel compounds | TANABE SEIYAKU CO., LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| EP-1701933-A1 | NOVEL COMPOUNDS | TANABE SEIYAKU CO., LTD. (JP) | 2006-09-20 | — | — | EP | disclosed |
| WO-2005061440-A1 | NOVEL COMPOUNDS | TANABE SEIYAKU CO., LTD. (JP) | 2005-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043113-A1 | Novel compounds | VCAM1, ICAM1, EPCAM | ITGA4 762/4885ITGB1 198/4885ITGB2 167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.