Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 6/20 | 0.57 |
| ▸ | MMP2 | P08253 | 6/20 | 0.57 |
| ▸ | MMP9 | P14780 | 6/20 | 0.57 |
| ▸ | EGFR | P00533 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | TGM2 | P21980 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649072 | 1.00 | MMP1 (0.57) | MMP1MMP2MMP9EGFRKMT2A | |
| SCHEMBL4647289 | 0.94 | MMP1 (0.61) | MMP1MMP2MMP9EGFRKMT2A | |
| SCHEMBL4648073 | 0.89 | MAPT (0.56) | MMP1MMP2MMP9EGFRKMT2A | |
| SCHEMBL9277123 | 0.89 | MAPT (0.56) | MMP1MMP2MMP9EGFRKMT2A | |
| SCHEMBL3986444 | 0.89 | MAPT (0.56) | MMP1MMP2MMP9EGFRKMT2A | |
| SCHEMBL4646526 | 0.85 | MAPT (0.57) | MMP1MMP2MMP9EGFRKMT2A | |
| SCHEMBL4646521 | 0.85 | MAPT (0.57) | MMP1MMP2MMP9EGFRKMT2A | |
| SCHEMBL4645241 | 0.84 | MMP1 (0.64) | MMP1MMP2MMP9EGFRKMT2A | |
| SCHEMBL4647865 | 0.84 | MMP1 (0.57) | MMP1MMP2MMP9EGFRKMT2A | |
| SCHEMBL4647868 | 0.84 | MMP1 (0.57) | MMP1MMP2MMP9EGFRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957459-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063702-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |