Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MMP1 | P03956 | 5/20 | 0.56 |
| ▸ | MMP2 | P08253 | 5/20 | 0.56 |
| ▸ | MMP9 | P14780 | 5/20 | 0.56 |
| ▸ | MAOB | P27338 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.56 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9277123 | 1.00 | MAPT (0.56) | MAPTALDH1A1MMP1MMP2MMP9 | |
| SCHEMBL4648073 | 1.00 | MAPT (0.56) | MAPTALDH1A1MMP1MMP2MMP9 | |
| SCHEMBL3040573 | 0.90 | ALDH1A1 (0.64) | MAPTALDH1A1MMP1MMP2MMP9 | |
| SCHEMBL4646465 | 0.89 | MAOA (0.51) | MAPTALDH1A1MMP1MMP2MMP9 | |
| SCHEMBL3035626 | 0.89 | MMP1 (0.61) | MAPTALDH1A1MMP1MMP2MMP9 | |
| SCHEMBL3035627 | 0.89 | MMP1 (0.61) | MAPTALDH1A1MMP1MMP2MMP9 | |
| SCHEMBL4644727 | 0.89 | MAPT (0.61) | MAPTALDH1A1MMP1MMP2MMP9 | |
| SCHEMBL4647289 | 0.89 | MMP1 (0.61) | MAPTALDH1A1MMP1MMP2MMP9 | |
| SCHEMBL4646521 | 0.89 | MAPT (0.57) | MAPTALDH1A1MMP1MMP2MMP9 | |
| SCHEMBL4649065 | 0.89 | MMP1 (0.57) | MAPTALDH1A1MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9055743-B2 | Alpha, beta-unsaturated imines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-16 | — | — | US | disclosed |
| CN-103476749-A | Alpha,beta-unsaturated imines | BAYER IP GMBH | 2013-12-25 | — | — | CN | disclosed |
| US-20130310254-A1 | Alpha, beta-unsaturated imines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-11-21 | — | — | US | disclosed |
| EP-2646413-A1 | ALPHA,BETA-UNSATURATED IMINES | Bayer Intellectual Property GmbH (DE) | 2013-10-09 | — | — | EP | disclosed |
| WO-2012072489-A1 | ALPHA,BETA-UNSATURATED IMINES | BAYER CROPSCIENCE AG (DE) | 2012-06-07 | — | — | WO | disclosed |
| WO-2009064031-A1 | ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-05-22 | — | — | WO | disclosed |
| EP-1957459-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063702-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130310254-A1 | Alpha, beta-unsaturated imines | TTPA, ECH1, GSTO1 | MAPT 4018/4885ALDH1A1 611/4885MMP1 2191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.