SCHEMBL4649083

SCHEMBL4649083

CC(C)CCCN(c1ccccc1)c1ccc(N)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
ALDH1A1 P00352 3/20 0.46
CYP3A4 P08684 3/20 0.46
KDM4E B2RXH2 2/20 0.46
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
MAPT P10636 1/20 0.46
SIGMAR1 Q99720 2/20 0.40
AOC3 Q16853 1/20 0.37
POLB P06746 1/20 0.36
APOBEC3A P31941 1/20 0.36
APOBEC3G Q9HC16 1/20 0.36
CYP2C8 P10632 1/20 0.36
CYP2C18 P33260 1/20 0.36
MAPK1 P28482 2/20 0.36
PSMD14 O00487 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL28942758 0.90 TDP1 (0.48) TDP1L3MBTL1ALDH1A1CYP3A4KDM4E
SCHEMBL87643 0.89 SIGMAR1 (0.46) L3MBTL1ALDH1A1KDM4ESIGMAR1AOC3
SCHEMBL15423270 0.84 SIGMAR1 (0.45) L3MBTL1KDM4ESIGMAR1AOC3POLB
SCHEMBL27689418 0.82 SIGMAR1 (0.44) L3MBTL1KDM4ESIGMAR1POLBAPOBEC3A
SCHEMBL3894942 0.82 TDP1 (0.52) TDP1L3MBTL1ALDH1A1CYP3A4KDM4E
SCHEMBL18979908 0.82 CYP3A4 (0.56) TDP1L3MBTL1ALDH1A1CYP3A4KDM4E
SCHEMBL2444795 0.81 ALDH1A1 (0.55) TDP1L3MBTL1ALDH1A1CYP3A4KDM4E
SCHEMBL28942753 0.80 ALDH1A1 (0.50) TDP1L3MBTL1ALDH1A1CYP3A4KDM4E
SCHEMBL18979892 0.80 CYP3A4 (0.62) TDP1L3MBTL1ALDH1A1CYP3A4KDM4E
SCHEMBL2440814 0.79 ALDH1A1 (0.53) TDP1L3MBTL1ALDH1A1CYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108191640-A A kind of highly efficiency compositional polymerization inhibitor and its application in acroleic acid polymerization is inhibited 万华化学集团股份有限公司 2018-06-22 CN claimed
EP-1960345-A1 ALKYLATION OF N' -PHENYL-N-ALKYLPHENYLENEDIAMINES IN IONIC LIQUID, N' -PHENYL-N-ALKYL(ALKYLPHENYLENE) DIAMINES PRODUCED THEREBY, AND LUBRICANT COMPOSITIONS CONTAINING SAME CHEMTURA CORPORATION (US) 2008-08-27 EP disclosed
WO-2007070282-A1 ALKYLATION OF N' -PHENYL-N-ALKYLPHENYLENEDIAMINES IN IONIC LIQUID, N' -PHENYL-N-ALKYL(ALKYLPHENYLENE) DIAMINES PRODUCED THEREBY, AND LUBRICANT COMPOSITIONS CONTAINING SAME CHEMTURA CORPORATION (US) 2007-06-21 WO disclosed
US-3954702-A VULCANIZATION DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1976-05-04 US disclosed