Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | CTSV | O60911 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | PPIA | P62937 | 1/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15942070 | 0.90 | CYP19A1 (0.65) | MEN1KMT2AMAPTCYP19A1ALDH1A1 | |
| SCHEMBL28216463 | 0.89 | CYP19A1 (0.57) | MEN1KMT2AMAPTCYP19A1ALDH1A1 | |
| SCHEMBL20581857 | 0.89 | KMT2A (0.58) | MEN1KMT2AMAPTCYP19A1ALDH1A1 | |
| SCHEMBL2393588 | 0.87 | CYP19A1 (0.56) | MEN1KMT2AMAPTCYP19A1ALDH1A1 | |
| SCHEMBL1319458 | 0.87 | CTSV (0.63) | MEN1KMT2AMAPTCYP19A1ALDH1A1 | |
| SCHEMBL2297894 | 0.86 | MEN1 (0.66) | MEN1KMT2AMAPTCYP19A1ALDH1A1 | |
| SCHEMBL6566866 | 0.86 | CYP19A1 (0.59) | MEN1KMT2AMAPTCYP19A1ALDH1A1 | |
| SCHEMBL6564411 | 0.86 | MAPT (0.51) | MEN1KMT2AMAPTCYP19A1ALDH1A1 | |
| SCHEMBL3949981 | 0.85 | MEN1 (0.58) | MEN1KMT2AMAPTCYP19A1ALDH1A1 | |
| SCHEMBL4649097 | 0.85 | MEN1 (0.60) | MEN1KMT2AMAPTCYP19A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105820078-A | 2-benzyloxy-5-[3-(2,5-diethoxy-4-methanesulfonyl-benzyl)-ureido]- methyl benzoate new compound and preparation method and application thereof | 齐鲁工业大学 | 2016-08-03 | — | — | CN | disclosed |
| US-20040259912-A1 | Benzine derivatives, process for preparing the same and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-12-23 | — | — | US | disclosed |
| EP-1437344-A1 | BENZENE DERIVATIVES,PROCESS FOR PREPARING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2004-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259912-A1 | Benzine derivatives, process for preparing the same and use thereof | HRH4, HRH2, HRH1 | MEN1 4143/4885KMT2A 3137/4885MAPT 4743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.