Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.42 |
| ▸ | VCP | P55072 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4884203 | 0.98 | RAD52 (0.50) | RAD52SIGMAR1CARM1PRMT6PRMT8 | |
| SCHEMBL12838201 | 0.86 | RAD52 (0.60) | RAD52SIGMAR1CARM1PRMT6PRMT8 | |
| SCHEMBL4281737 | 0.84 | RAD52 (0.63) | RAD52SIGMAR1CARM1PRMT6PRMT8 | |
| SCHEMBL3446318 | 0.82 | RAD52 (0.72) | RAD52SIGMAR1CARM1PRMT6PRMT8 | |
| SCHEMBL3605906 | 0.78 | RAD52 (0.53) | RAD52SIGMAR1CARM1PRMT6PRMT8 | |
| SCHEMBL3585953 | 0.77 | RAD52 (0.51) | RAD52SIGMAR1CARM1PRMT6PRMT8 | |
| Hydrochloric Acid SCHEMBL3598388 | 0.77 | RAD52 (0.51) | RAD52SIGMAR1CARM1PRMT6PRMT8 | |
| SCHEMBL24333102 | 0.76 | RAD52 (0.59) | RAD52SIGMAR1CARM1PRMT6PRMT8 | |
| SCHEMBL20402780 | 0.76 | RAD52 (0.50) | RAD52SIGMAR1CARM1PRMT6PRMT8 | |
| SCHEMBL6973435 | 0.72 | RAD52 (0.55) | RAD52SIGMAR1CARM1PRMT6PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269170-A1 | Novel 2,4-Dianilinopyrimidine Derivatives, the Preparation Thereof, Their Use as Medicaments, Pharmaceutical Compositions and, in Particular, as IKK Inhibitors | SANOFI-AVENTIS (FR) | 2008-10-30 | — | — | US | disclosed |
| EP-1904479-A2 | NOVEL 2,4-DIANILINOPYRIMIDINE DERIVATIVES, THE PREPARATION THEREOF, THEIR USE AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND, IN PARTICULAR, AS IKK INHIBITORS | Sanofi-Aventis (FR) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007006926-A2 | NOVEL 2,4-DIANILINOPYRIMIDINE DERIVATIVES, THE PREPARATION THEREOF, THEIR USE AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND, IN PARTICULAR, AS IKK INHIBITORS | SANOFI-AVENTIS (FR) | 2007-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269170-A1 | Novel 2,4-Dianilinopyrimidine Derivatives, the Preparation Thereof, Their Use as Medicaments, Pharmaceutical Compositions and, in Particular, as IKK Inhibitors | NFKBIA, IKBKB, IKBKE | RAD52 1014/4885SIGMAR1 4101/4885CARM1 2507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.