Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 13/20 | 0.74 |
| ▸ | GABRD | O14764 | 13/20 | 0.74 |
| ▸ | GABRA1 | P14867 | 13/20 | 0.74 |
| ▸ | GABRB1 | P18505 | 13/20 | 0.74 |
| ▸ | GABRG2 | P18507 | 13/20 | 0.74 |
| ▸ | GABRB3 | P28472 | 13/20 | 0.74 |
| ▸ | GABRA5 | P31644 | 13/20 | 0.74 |
| ▸ | GABRA3 | P34903 | 13/20 | 0.74 |
| ▸ | GABRA2 | P47869 | 13/20 | 0.74 |
| ▸ | GABRB2 | P47870 | 13/20 | 0.74 |
| ▸ | GABRA4 | P48169 | 13/20 | 0.74 |
| ▸ | GABRE | P78334 | 13/20 | 0.74 |
| ▸ | GABRA6 | Q16445 | 13/20 | 0.74 |
| ▸ | GABRG1 | Q8N1C3 | 13/20 | 0.74 |
| ▸ | GABRG3 | Q99928 | 13/20 | 0.74 |
| ▸ | GABRQ | Q9UN88 | 13/20 | 0.74 |
| ▸ | TNKS | O95271 | 3/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4650588 | 0.87 | GABRP (0.82) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4988784 | 0.85 | MAPT (0.77) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4993162 | 0.85 | EGFR (0.77) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| 6-Bromoflavone SCHEMBL4449962 | 0.84 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4650552 | 0.82 | CSNK2A2 (0.74) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4990151 | 0.81 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4989940 | 0.81 | APP (0.71) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11633093 | 0.81 | TNKS (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4990064 | 0.81 | APP (0.71) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4990126 | 0.80 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| EP-2730431-B1 | Rubber composition and tire with rubber containing flavone | GOODYEAR TIRE & RUBBER (US) | 2017-06-28 | — | — | EP | disclosed |
| US-20140135433-A1 | TIRE WITH RUBBER CONTAINING FLAVONE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2014-05-15 | — | — | US | disclosed |
| EP-2730431-A1 | Rubber composition and tire with rubber containing flavone | The Goodyear Tire & Rubber Company (US) | 2014-05-14 | — | — | EP | disclosed |
| EP-1391327-B1 | Tire with rubber containing flavone | GOODYEAR TIRE & RUBBER (US) | 2008-09-03 | — | — | EP | disclosed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | disclosed |
| EP-1391327-A1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2004-02-25 | — | — | EP | disclosed |
| WO-2003057210-A1 | COMPOSITIONS AND METHODS FOR INCREASING CELL PROLIFERATION COMPRISING A FLAVONOID | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2003-07-17 | — | — | WO | disclosed |
| US-20030125264-A1 | Methods For Treating Wounds | KIMBERLY-CLARK WORLDWIDE, INC. | 2003-07-03 | — | — | US | disclosed |
| WO-1998027080-A1 | CHROMONES USEFUL AS FUNGICIDES | AGREVO UK LIMITED (GB) | 1998-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125264-A1 | Methods For Treating Wounds | FGF2, MMP1, FIBP | GABRP 4122/4885GABRD 4414/4885GABRA1 4698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.