Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 8/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.59 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11289655 | 0.82 | HPGD (0.73) | LCKHPGDCYP3A4MEN1KMT2A | |
| SCHEMBL4649187 | 0.81 | HPGD (0.74) | LCKHPGDCYP3A4MEN1KMT2A | |
| SCHEMBL9528168 | 0.80 | LCK (0.78) | LCKHPGDCYP3A4MEN1KMT2A | |
| SCHEMBL253522 | 0.80 | HPGD (0.78) | LCKHPGDCYP3A4MEN1KMT2A | |
| SCHEMBL5320080 | 0.77 | KDM4E (0.81) | LCKHPGDCYP3A4MEN1KMT2A | |
| SCHEMBL29149160 | 0.76 | HPGD (0.55) | LCKHPGDCYP3A4MEN1KMT2A | |
| SCHEMBL4649397 | 0.75 | AR (0.72) | LCKHPGDCYP3A4MEN1KMT2A | |
| SCHEMBL30089725 | 0.75 | AR (0.72) | LCKHPGDCYP3A4MEN1KMT2A | |
| SCHEMBL7121068 | 0.75 | HPGD (0.72) | LCKHPGDCYP3A4MEN1KMT2A | |
| Eupatorin SCHEMBL22394524 | 0.74 | CYP1A1 (0.79) | LCKHPGDCYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391327-B1 | Tire with rubber containing flavone | GOODYEAR TIRE & RUBBER (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1391327-A1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2004-02-25 | — | — | EP | disclosed |