Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 3/20 | 0.71 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HTR7 | P34969 | 4/20 | 0.55 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.52 |
| ▸ | XDH | P47989 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9725381 | 0.95 | RAB9A (0.71) | MPORAB9ALMNAALDH1A1MAPT | |
| SCHEMBL4419395 | 0.89 | MEN1 (0.63) | MPORAB9ALMNAALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL9725349 | 0.88 | RAB9A (0.64) | MPORAB9ALMNAALDH1A1MAPT | |
| SCHEMBL7258664 | 0.85 | RAB9A (0.58) | MPORAB9ALMNAALDH1A1MAPT | |
| SCHEMBL30947438 | 0.84 | LMNA (0.78) | RAB9ALMNAALDH1A1MAPTHPGD | |
| SCHEMBL7272271 | 0.84 | RAB9A (0.57) | MPORAB9ALMNAALDH1A1MAPT | |
| SCHEMBL1838349 | 0.83 | RAB9A (0.70) | RAB9ALMNAALDH1A1MAPTHPGD | |
| SCHEMBL25315525 | 0.82 | RAB9A (0.68) | RAB9ALMNAALDH1A1MAPTHPGD | |
| SCHEMBL11139092 | 0.82 | RAB9A (0.68) | RAB9ALMNAALDH1A1MAPTHPGD | |
| SCHEMBL8132581 | 0.82 | RAB9A (0.68) | RAB9ALMNAALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960370-A1 | PYRIDIAZINONE DERIVATIVES FOR TUMOUR TREATMENT | Merck Patent GmbH (DE) | 2008-08-27 | — | — | EP | claimed |
| WO-2007065518-A1 | PYRIDIAZINONE DERIVATIVES FOR TUMOUR TREATMENT | MERCK PATENT GMBH (DE) | 2007-06-14 | — | — | WO | claimed |
| EP-1960370-A1 | PYRIDIAZINONE DERIVATIVES FOR TUMOUR TREATMENT | Merck Patent GmbH (DE) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007065518-A1 | PYRIDIAZINONE DERIVATIVES FOR TUMOUR TREATMENT | MERCK PATENT GMBH (DE) | 2007-06-14 | — | — | WO | disclosed |