Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 7/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649139 | 0.87 | NAMPT (0.43) | GLATDP1PRMT5WDR77F10 | |
| SCHEMBL4649150 | 0.84 | F2R (0.36) | TDP1HTR1AHTR7PRMT5WDR77 | |
| SCHEMBL4650297 | 0.79 | TDP1 (0.47) | TDP1CYP2C19USP2ALDH1A1 | |
| SCHEMBL4650250 | 0.79 | CFTR (0.43) | TDP1MMP8MMP3USP2ALDH1A1 | |
| SCHEMBL4649495 | 0.78 | PRMT5 (0.46) | PRMT5WDR77 | |
| SCHEMBL25382952 | 0.75 | HTR1A (0.56) | GLAHTR1AHTR7MMP8MMP3 | |
| SCHEMBL15152498 | 0.75 | HTR1A (0.56) | GLAHTR1AHTR7MMP8MMP3 | |
| SCHEMBL16411288 | 0.69 | FKBP1A (0.47) | HTR1AHTR7USP2ALDH1A1MAPT | |
| SCHEMBL1061859 | 0.69 | TDP1 (0.49) | TDP1HTR1AHTR7ALDH1A1MAPT | |
| SCHEMBL4922008 | 0.68 | HDAC8 (0.51) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904495-A2 | MUSCARINIC RECEPTOR ANTAGONISTS | Ranbaxy Laboratories Limited (IN) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007007281-A2 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |