SCHEMBL4649637

SCHEMBL4649637

COc1ccc(-c2oc3ccccc3c(=O)c2O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 1.00
CYP3A4 P08684 8/20 1.00
ALDH1A1 P00352 7/20 1.00
HSD17B10 Q99714 6/20 1.00
MEN1 O00255 7/20 0.75
KMT2A Q03164 7/20 0.75
TP53 P04637 6/20 0.75
HPGD P15428 5/20 0.75
MAPT P10636 5/20 0.75
CASP1 P29466 2/20 0.75
CASP7 P55210 2/20 0.75
ABCG2 Q9UNQ0 3/20 0.74
MAPK1 P28482 4/20 0.74
TSHR P16473 3/20 0.74
ALOX12 P18054 3/20 0.74
CYP2D6 P10635 2/20 0.74
CYP2C9 P11712 2/20 0.74
CYP2C19 P33261 2/20 0.74
TDP1 Q9NUW8 1/20 0.74
LMNA P02545 3/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30309497 1.00 KDM4E (1.00) KDM4ECYP3A4ALDH1A1HSD17B10MEN1
SCHEMBL2746872 0.88 MEN1 (0.90) KDM4ECYP3A4ALDH1A1HSD17B10MEN1
SCHEMBL4650608 0.86 CSNK2A2 (0.82) KDM4ECYP3A4ALDH1A1HSD17B10MEN1
SCHEMBL4650077 0.86 CYP3A4 (1.00) KDM4ECYP3A4ALDH1A1HSD17B10MEN1
SCHEMBL30807156 0.86 CYP3A4 (1.00) KDM4ECYP3A4ALDH1A1HSD17B10MEN1
Kaempferide SCHEMBL19097707 0.85 ABCB1 (0.79) KDM4ECYP3A4ALDH1A1HSD17B10MEN1
SCHEMBL4650702 0.85 ABCG2 (1.00) KDM4ECYP3A4ALDH1A1HSD17B10MEN1
SCHEMBL4649962 0.85 KDM4E (1.00) KDM4ECYP3A4ALDH1A1HSD17B10MEN1
SCHEMBL30667386 0.85 KDM4E (1.00) KDM4ECYP3A4ALDH1A1HSD17B10MEN1
Flavonol SCHEMBL7691888 0.85 KDM4E (0.72) KDM4ECYP3A4ALDH1A1HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6872771-B1 Tire with rubber containing flavone THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-03-29 US claimed
EP-1109800-A1 NOVEL CDK INHIBITORS HAVING FLAVONE STRUCTURE LG CHEMICAL LIMITED (KR) 2001-06-27 EP claimed
WO-2000012496-A1 NOVEL CDK INHIBITORS HAVING FLAVONE STRUCTURE LG CHEMICAL LTD. (KR) 2000-03-09 WO claimed
US-12368049-B2 Protective film agent and processing method of workpiece DISCO CORPORATION (JP) 2025-07-22 US disclosed
US-20240290624-A1 PROTECTIVE FILM, PROTECTIVE FILM AGENT, AND METHOD OF PROCESSING WORKPIECE DISCO CORPORATION (JP) 2024-08-29 US disclosed
US-20230091496-A1 PROTECTIVE FILM AGENT AND PROCESSING METHOD OF WORKPIECE DISCO CORPORATION (JP) 2023-03-23 US disclosed
CN-115785742-A Protective film agent and method for processing processed object 株式会社迪思科 2023-03-14 CN disclosed
WO-2020022961-A1 INHIBITORS OF IRES PORTION OF AN ENTEROVIRUS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2020-01-30 WO disclosed
EP-2730431-B1 Rubber composition and tire with rubber containing flavone GOODYEAR TIRE & RUBBER (US) 2017-06-28 EP disclosed
US-20140135433-A1 TIRE WITH RUBBER CONTAINING FLAVONE THE GOODYEAR TIRE & RUBBER COMPANY (US) 2014-05-15 US disclosed
EP-2730431-A1 Rubber composition and tire with rubber containing flavone The Goodyear Tire & Rubber Company (US) 2014-05-14 EP disclosed
EP-1391327-A1 Tire with rubber containing flavone THE GOODYEAR TIRE & RUBBER COMPANY (US) 2004-02-25 EP disclosed
US-6677350-B1 ADMINISTERING CHALCONE-LIKE VINYLCARBONYL COMPOUNDS TO PREVENT OR TREAT MYCOBACTERIUM INFECTIONS/TUBERCULOSIS ADVANCED LIFE SCIENCES, INC. 2004-01-13 US disclosed
WO-2003057210-A1 COMPOSITIONS AND METHODS FOR INCREASING CELL PROLIFERATION COMPRISING A FLAVONOID KIMBERLY-CLARK WORLDWIDE, INC. (US) 2003-07-17 WO disclosed
US-20030125264-A1 Methods For Treating Wounds KIMBERLY-CLARK WORLDWIDE, INC. 2003-07-03 US disclosed
US-6500846-B1 2-(4-CHLOROPHENYL)-7-METHOXYCHROMEN-4-ONE, AS CYCLIN-DEPENDENT KINASE INHIBITORS, USED AS ANTICARCINOGENIC AGENTS OR FOR PROPHYLAXIS OF NEURODEGENERATIVE DISEASE LG CHEMICAL, LTD. (KR) 2002-12-31 US disclosed
EP-1217995-A2 ANTI-MYCOBACTERIUM COMPOSITIONS AND METHODS OF PREPARING AND USING SAME Advanced Life Sciences Inc. (US) 2002-07-03 EP disclosed
EP-1109800-A1 NOVEL CDK INHIBITORS HAVING FLAVONE STRUCTURE LG CHEMICAL LIMITED (KR) 2001-06-27 EP disclosed
WO-2001021164-A2 ANTI-MYCOBACTERIUM COMPOSITIONS AND METHODS OF PREPARING AND USING SAME ADVANCED LIFE SCIENCES, INC. (US) 2001-03-29 WO disclosed
WO-2000012496-A1 NOVEL CDK INHIBITORS HAVING FLAVONE STRUCTURE LG CHEMICAL LTD. (KR) 2000-03-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030125264-A1 Methods For Treating Wounds FGF2, MMP1, FIBP KDM4E 2309/4885CYP3A4 3010/4885ALDH1A1 2440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.