Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 10/20 | 1.00 |
| ▸ | TP53 | P04637 | 9/20 | 1.00 |
| ▸ | MEN1 | O00255 | 9/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 9/20 | 1.00 |
| ▸ | MAPT | P10636 | 8/20 | 1.00 |
| ▸ | HPGD | P15428 | 6/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 4/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 4/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 4/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 4/20 | 1.00 |
| ▸ | ALOX12 | P18054 | 4/20 | 1.00 |
| ▸ | TSHR | P16473 | 3/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.76 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.76 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.76 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30667386 | 1.00 | KDM4E (1.00) | KDM4ECYP3A4TP53MEN1KMT2A | |
| SCHEMBL5139273 | 0.90 | CYP3A4 (0.81) | KDM4ECYP3A4TP53MEN1KMT2A | |
| SCHEMBL5138118 | 0.90 | MAPT (0.84) | KDM4ECYP3A4TP53MEN1KMT2A | |
| SCHEMBL4649960 | 0.86 | KDM4E (0.76) | KDM4ECYP3A4TP53MEN1KMT2A | |
| SCHEMBL17786490 | 0.85 | MAPT (0.77) | KDM4ECYP3A4TP53MEN1KMT2A | |
| SCHEMBL4649637 | 0.85 | KDM4E (1.00) | KDM4ECYP3A4TP53MEN1KMT2A | |
| SCHEMBL30309497 | 0.85 | KDM4E (1.00) | KDM4ECYP3A4TP53MEN1KMT2A | |
| SCHEMBL10037934 | 0.85 | MAPT (0.76) | KDM4ECYP3A4TP53MEN1KMT2A | |
| SCHEMBL10068185 | 0.85 | KDM4E (0.73) | KDM4ECYP3A4TP53MEN1KMT2A | |
| SCHEMBL9665959 | 0.84 | MAPT (0.73) | KDM4ECYP3A4TP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| JP-2003504327-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | claimed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | claimed |
| US-20250263774-A1 | DISCOVERING NEW XENOBIOTIC SUBSTRATES OF AN UDP-GLYCOSYLTRANSFERASE WITH A HIGH-THROUGHPUT METHOD | UNIV NORTH TEXAS (US) | 2025-08-21 | — | — | US | disclosed |
| CN-119954794-A | Flavonol derivative containing benzothiazole, and preparation method and application thereof | 贵州大学 | 2025-05-09 | — | — | CN | disclosed |
| EP-4536210-A2 | FLAVONOID COMPOUNDS AND METHODS AND MATERIALS FOR USING FLAVONOID COMPOUNDS TO TREAT FIBROTIC CONDITIONS | Mayo Foundation for Medical Education and Research (US) | 2025-04-16 | — | — | EP | disclosed |
| CN-119365193-A | Flavonoid compounds and methods and materials for treating fibrotic disorders using flavonoid compounds | 梅约医学教育与研究基金会 | 2025-01-24 | — | — | CN | disclosed |
| CN-117561081-A | Application of CYP450 inhibitor in inhibiting or killing mites and treating xerophthalmia | 广州珍实视界生物医药科技有限公司 | 2024-02-13 | — | — | CN | disclosed |
| WO-2023244619-A2 | FLAVONOID COMPOUNDS AND METHODS AND MATERIALS FOR USING FLAVONOID COMPOUNDS TO TREAT FIBROTIC CONDITIONS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2023-12-21 | — | — | WO | disclosed |
| CN-115948362-A | Oxygen methyltransferase participating in biosynthesis of polymethoxyflavone in citrus peel, coding gene, amplification primer pair and application | 浙江大学 | 2023-04-11 | — | — | CN | disclosed |
| EP-2730431-B1 | Rubber composition and tire with rubber containing flavone | GOODYEAR TIRE & RUBBER (US) | 2017-06-28 | — | — | EP | disclosed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | disclosed |
| EP-1391327-A1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2004-02-25 | — | — | EP | disclosed |
| WO-2003057210-A1 | COMPOSITIONS AND METHODS FOR INCREASING CELL PROLIFERATION COMPRISING A FLAVONOID | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2003-07-17 | — | — | WO | disclosed |
| US-20030125264-A1 | Methods For Treating Wounds | KIMBERLY-CLARK WORLDWIDE, INC. | 2003-07-03 | — | — | US | disclosed |
| US-6555523-B1 | Such as 3',4'-diacetoxy-5,6,7-trimethoxyflavone or naringin in the treatment HIV, picornavirus, and/or respiratory virus | CASCADE ESTATES LTD. (MU) | 2003-04-29 | — | — | US | disclosed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | disclosed |
| EP-0065123-A1 | Hardly soluble salts of aminoglycoside antibiotics | MERCK PATENT GmbH (DE) | 1982-11-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125264-A1 | Methods For Treating Wounds | FGF2, MMP1, FIBP | KDM4E 2309/4885CYP3A4 3010/4885TP53 841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.