Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649691 | 1.00 | MAOB (0.51) | MAOBLMNAHTTNR1I2PGR | |
| SCHEMBL5474591 | 0.88 | LMNA (0.53) | MAOBLMNAHTTNR1I2PGR | |
| SCHEMBL5474595 | 0.88 | LMNA (0.53) | MAOBLMNAHTTNR1I2PGR | |
| SCHEMBL30200945 | 0.86 | MCL1 (0.54) | MAOBLMNAHTTNR1I2PGR | |
| SCHEMBL13845315 | 0.83 | CYP2C9 (0.40) | MAOBLMNAHTTNR1I2PGR | |
| SCHEMBL4056507 | 0.83 | CYP2C9 (0.40) | MAOBLMNAHTTNR1I2PGR | |
| SCHEMBL4056505 | 0.83 | CYP2C9 (0.40) | MAOBLMNAHTTNR1I2PGR | |
| SCHEMBL15630823 | 0.83 | LMNA (0.43) | MAOBLMNAHTTNR1I2PGR | |
| SCHEMBL11833868 | 0.82 | MAPT (0.59) | MAOBLMNAHTTNR1I2PGR | |
| SCHEMBL5468473 | 0.82 | LMNA (0.49) | MAOBLMNAHTTNR1I2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368287-B1 | PROCESS FOR A HOMOGENEOUSLY CATALYZED C-C COUPLING REACTION | DSM IP ASSETS BV (NL) | 2008-03-26 | — | — | EP | disclosed |