Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.44 |
| ▸ | TFEB | P19484 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5474595 | 1.00 | LMNA (0.53) | LMNAHTTNR1I2PGRCYP3A4 | |
| SCHEMBL5457639 | 0.93 | CA1 (0.51) | LMNAHTTNR1I2PGRCYP3A4 | |
| SCHEMBL5468478 | 0.93 | LMNA (0.49) | LMNAHTTNR1I2PGRCYP3A4 | |
| SCHEMBL5468473 | 0.93 | LMNA (0.49) | LMNAHTTNR1I2PGRCYP3A4 | |
| SCHEMBL5457635 | 0.93 | CA1 (0.51) | LMNAHTTNR1I2PGRCYP3A4 | |
| SCHEMBL29262006 | 0.93 | LMNA (0.49) | LMNAHTTNR1I2PGRCYP3A4 | |
| SCHEMBL18843948 | 0.90 | LMNA (0.52) | LMNAHTTNR1I2PGRCYP3A4 | |
| SCHEMBL11833864 | 0.90 | MAPT (0.59) | LMNAHTTNR1I2PGRCYP3A4 | |
| SCHEMBL11833868 | 0.90 | MAPT (0.59) | LMNAHTTNR1I2PGRCYP3A4 | |
| SCHEMBL18045862 | 0.88 | LMNA (0.51) | LMNAHTTNR1I2PGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043088-A1 | PROCESS FOR PREPARING LACIDIPINE | DR. REDDY'S LABORATORIES LIMITED (IN) | 2007-02-22 | — | — | US | claimed |
| US-20070043088-A1 | PROCESS FOR PREPARING LACIDIPINE | DR. REDDY'S LABORATORIES LIMITED (IN) | 2007-02-22 | — | — | US | disclosed |
| US-20070043088-A1 | PROCESS FOR PREPARING LACIDIPINE | DR. REDDY'S LABORATORIES LIMITED (IN) | 2007-02-22 | — | — | US | disclosed |
| US-20070043088-A1 | PROCESS FOR PREPARING LACIDIPINE | DR. REDDY'S LABORATORIES LIMITED (IN) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043088-A1 | PROCESS FOR PREPARING LACIDIPINE | CHRNA5, CACNA1I, CHRNA3 | LMNA 1328/4885HTT 2248/4885NR1I2 2405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.