SCHEMBL4649769

SCHEMBL4649769

CCn1c(O)cc(C)c(CS(=O)(=O)O)c1=O

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.38
LMNA P02545 2/20 0.37
POLB P06746 2/20 0.37
SRC P12931 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
ALDH1A1 P00352 1/20 0.32
RAB9A P51151 1/20 0.32
KDM5A P29375 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
BRPF1 P55201 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9161398 0.88 KDM4E (0.40) KDM4ELMNAPOLBALDH1A1
SCHEMBL8345205 0.86 KDM4E (0.30) KDM4E
SCHEMBL9160763 0.85 ALDH1A1 (0.41) KDM4ELMNAL3MBTL1ALDH1A1
SCHEMBL11326254 0.85 KDM4E (0.39) KDM4ELMNAPOLBSRCL3MBTL1
SCHEMBL9157985 0.85 MEN1 (0.40) KDM4ELMNAALDH1A1
SCHEMBL9162658 0.84 SRC (0.34) KDM4ELMNAPOLBSRCL3MBTL1
SCHEMBL8751482 0.84
SCHEMBL10416671 0.83 KDM4E (0.34) KDM4EPOLBL3MBTL1ALDH1A1
SCHEMBL8926647 0.82 KMT2A (0.43) KDM4ELMNAPOLBL3MBTL1ALDH1A1
SCHEMBL7891047 0.82 KDM4E (0.33) KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109054439-B Phthalocyanine azo-based double-chromophore bright green reactive dye and preparation method and application thereof 东华大学 2021-03-19 CN claimed
CN-116144195-B High-performance alkali-resistant yellow reactive dye and preparation method thereof 江苏德美科化工有限公司 2024-04-02 CN disclosed
CN-116144195-A High-performance alkali-resistant yellow reactive dye and preparation method thereof 江苏德美科化工有限公司 2023-05-23 CN disclosed
CN-109054439-B Phthalocyanine azo-based double-chromophore bright green reactive dye and preparation method and application thereof 东华大学 2021-03-19 CN disclosed
US-20170015829-A1 Novel Pyridone Dyes CLARIANT INTERNATIONAL LTD. (CH) 2017-01-19 US disclosed
US-20170015829-A1 Novel Pyridone Dyes CLARIANT INTERNATIONAL LTD. (CH) 2017-01-19 US disclosed
US-20170018599-A1 Pyridone Dye Composition CLARIANT INTERNATIONAL LTD. (CH) 2017-01-19 US disclosed
US-20170018599-A1 Pyridone Dye Composition CLARIANT INTERNATIONAL LTD. (CH) 2017-01-19 US disclosed
WO-2015135633-A1 NOVEL PYRIDONE DYES CLARIANT INTERNATIONAL LTD (CH) 2015-09-17 WO disclosed
WO-2015135634-A1 PYRIDONE DYE COMPOSITION CLARIANT INTERNATIONAL LTD (CH) 2015-09-17 WO disclosed
US-4325869-A CONTAINING A PYRIMIDINE RING AND ONE OR MORE AZO GROUPS CIBA-GEIGY CORPORATION (US) 1982-04-20 US disclosed
US-4299764-A Azo reactive dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1981-11-10 US disclosed
US-4229171-A Process for the preparation of fiber-reactive dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1980-10-21 US disclosed
US-4228071-A Triazine containing fiber-reactive disazo dyestuffs CIBA-GEIGY CORPORATION (US) 1980-10-14 US disclosed
EP-0013936-A1 Reactive azo dyestuffs, their preparation and their use in dyeing materials containing hydroxyl groups and amide groups BAYER AG (DE) 1980-08-06 EP disclosed
US-4116624-A DISAZO DYES FOR NATURAL OR SYNTHETIC POLYAMIDES CIBA-GEIGY CORPORATION (US) 1978-09-26 US disclosed
US-4102880-A COLORFASTNESS, BRILLIANT GREENISH-YELLOW CIBA-GEIGY CORPORATION (US) 1978-07-25 US disclosed
US-4039523-A YELLOW CIBA-GEIGY AG (CH) 1977-08-02 US disclosed
US-4017477-A 3-Halogeno-6-hydroxy-pyridone-(2) azo dyestuffs CIBA-GEIGY AG (CH) 1977-04-12 US disclosed
US-3994906-A DYE COUPLERS CIBA-GEIGY AG (CH) 1976-11-30 US disclosed