SCHEMBL8345205

SCHEMBL8345205

CCn1c(O)cc(C)c(CS(=O)(=O)O)c1=O.Cc1cc(O)n(C)c(=O)c1S(C)(=O)=O

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4649769 0.86 KDM4E (0.38) KDM4E
SCHEMBL9449244 0.81 KDM4E (0.40) KDM4E
SCHEMBL9153890 0.81 TTR (0.32) KDM4E
SCHEMBL4651267 0.79 MAPK1 (0.42) KDM4E
SCHEMBL10953369 0.79 KDM4E (0.41) KDM4E
SCHEMBL9161398 0.79 KDM4E (0.40) KDM4E
SCHEMBL8751482 0.77
SCHEMBL9160763 0.76 ALDH1A1 (0.41) KDM4E
SCHEMBL9157985 0.76 MEN1 (0.40) KDM4E
SCHEMBL11326254 0.73 KDM4E (0.39) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5929217-A FOR DYEING OR PRINTING SUBSTRATES HAVING HYDROXYL GROUPS OR NITROGEN ATOMS BASF AKTIENGESELLSCHAFT (DE) 1999-07-27 US disclosed