SCHEMBL464977

SCHEMBL464977

O=C(O)c1ccc2c(C(=O)O)cccc2c1C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.55
NR4A2 P43354 1/20 0.55
NR4A3 Q92570 1/20 0.55
PRNP P04156 1/20 0.49
CDC25B P30305 3/20 0.48
PTPN1 P18031 1/20 0.47
ALDH1A1 P00352 2/20 0.46
ALOX15 P16050 1/20 0.46
TYMS P04818 1/20 0.44
WDR5 P61964 1/20 0.42
AKR1C3 P42330 1/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
KDM4E B2RXH2 4/20 0.41
HSD17B10 Q99714 3/20 0.41
HPGD P15428 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29996206 1.00 NR4A1 (0.55) NR4A1NR4A2NR4A3PRNPCDC25B
SCHEMBL31401786 1.00 NR4A1 (0.55) NR4A1NR4A2NR4A3PRNPCDC25B
SCHEMBL29420737 0.87 CYP1A2 (0.52) NR4A1NR4A2NR4A3CDC25BPTPN1
SCHEMBL48997 0.87 CYP1A2 (0.52) NR4A1NR4A2NR4A3CDC25BPTPN1
SCHEMBL6518298 0.86 NR4A1 (0.50) NR4A1NR4A2NR4A3PRNPCDC25B
SCHEMBL2174498 0.85 NR4A1 (0.48) NR4A1NR4A2NR4A3PRNPCDC25B
SCHEMBL10012443 0.84 NR4A1 (0.67) NR4A1NR4A2NR4A3PRNPCDC25B
SCHEMBL202564 0.84 CYP1A2 (0.50) NR4A1NR4A2NR4A3CDC25BPTPN1
SCHEMBL10397600 0.84 NR4A1 (0.74) NR4A1NR4A2NR4A3PRNPCDC25B
SCHEMBL5549583 0.84 CYP1A2 (0.50) NR4A1NR4A2NR4A3CDC25BPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 266 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3143067-B1 MULTIFUNCTIONAL POLYAMIDES FOR PROTECTIVE COATINGS HUNTSMAN ADVANCED MAT AMERICAS LLC (US) 2023-09-13 EP claimed
EP-3143067-A1 MULTIFUNCTIONAL POLYAMIDES FOR PROTECTIVE COATINGS Huntsman Advanced Materials Americas LLC (US) 2017-03-22 EP claimed
US-20170051100-A1 MULTIFUNCTIONAL POLYAMIDES FOR PROTECTIVE COATINGS HUNTSMAN ADVANCED MATERIALS AMERICAS LLC 2017-02-23 US claimed
CN-106414543-A Multifunctional polyamides for protective coatings 亨斯迈先进材料美国有限责任公司 2017-02-15 CN claimed
WO-2015175583-A1 MULTIFUNCTIONAL POLYAMIDES FOR PROTECTIVE COATINGS HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2015-11-19 WO claimed
US-8859806-B2 Process for purification of aryl carboxylic acids UNIVERSITY OF ALABAMA (US) 2014-10-14 US claimed
US-20130068996-A1 PROCESS FOR PURIFICATION OF ARYL CARBOXYLIC ACIDS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2013-03-21 US claimed
US-20100174111-A1 PROCESS FOR PURIFICATION OF ARYL CARBOXYLIC ACIDS UNIVERSITY OF ALABAMA 2010-07-08 US claimed
WO-2008151034-A1 IMPROVED PROCESS FOR PURIFICATION OF ARYL CARBOXYLIC ACIDS THE UNIVERSITY OF ALABAMA (US) 2008-12-11 WO claimed
US-20060014876-A1 Thermally conductive liquid crystalline polymer compositions and articles formed therefrom SOLVAY ADVANCED POLYMERS, LLC 2006-01-19 US claimed
EP-1537189-A1 THERMALLY CONDUCTIVE LIQUID CRYSTALLINE POLYMER COMPOSITIONS AND ARTICLES FORMED THEREFROM Solvay Advanced Polymers, L.L.C. (US) 2005-06-08 EP claimed
WO-2004022669-A1 THERMALLY CONDUCTIVE LIQUID CRYSTALLINE POLYMER COMPOSITIONS AND ARTICLES FORMED THEREFROM SOLVAY ADVANCED POLYMERS, LLC (US) 2004-03-18 WO claimed
US-5395870-A Styrene or acrylic polymer, polyamideimide elastomer, permanent antistatic property, molding materials ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1995-03-07 US claimed
EP-0409995-B1 VINYLIC RESIN COMPOSITION ASAHI CHEMICAL IND (JP) 1994-12-14 EP claimed
EP-0336856-B1 WITH MALEIMIDE GROUPS FUNCTIONALIZED AROMATIC POLYAMIDEIMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR PREPARING CROSS-LINKED POLYMERS CIBA-GEIGY AG (CH) 1993-03-03 EP claimed
EP-0360709-B1 PROCESS FOR THE PREPARATION OF THERMALLY STABLE COPOLYIMIDE AMIDES CONTAINING DIORGANOPOLYSILOXANE GROUPS CIBA-GEIGY AG (CH) 1992-12-16 EP claimed
EP-0334778-B1 AROMATIC POLYAMIDE-IMIDES FUNCTIONALISED WITH ALKENYLOXY GROUPS, A METHOD FOR THEIR PREPARATION AND THEIR USE TO PREPARE CROSSLINKED POLYMERS CIBA-GEIGY AG (CH) 1992-04-15 EP claimed
US-4985527-A Preparation of thermally stable copolyimidoamides containing diorganopolysiloxane recurring units RHONE-POULENC CHIMIE (FR) 1991-01-15 US claimed
US-4927899-A Alkenyloxylated aromatic polyamidoimides RHONE-POULENC CHIMIE (FR) 1990-05-22 US claimed
US-4927900-A Aromatic polyamidoimides having maleimido end groups RHONE-POULENC CHIMIE (FR) 1990-05-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100174111-A1 PROCESS FOR PURIFICATION OF ARYL CARBOXYLIC ACIDS DDC, AHR, PAH NR4A1 2446/4885NR4A2 2107/4885NR4A3 2723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.