Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.42 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | KDM6A | O15550 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.35 |
| ▸ | TAF1 | P21675 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6679850 | 0.82 | IDH1 (0.44) | BRD4BRD9EGFRSRCPOLB | |
| SCHEMBL27302249 | 0.82 | KDM4E (0.39) | BRD4BRD9KDM4ECYP2C9KDM6A | |
| SCHEMBL18585162 | 0.81 | PARP1 (0.34) | BRD4BRD9EGFRSRCPOLB | |
| SCHEMBL29868736 | 0.78 | BRD4 (0.33) | BRD4BRD9EGFRSRCPOLB | |
| SCHEMBL31186077 | 0.77 | KDM4E (0.44) | BRD4KDM4ECYP2C9POLBLMNA | |
| SCHEMBL29908842 | 0.75 | NOTUM (0.46) | KDM4EEGFRSRCLMNAALDH1A1 | |
| SCHEMBL1665468 | 0.75 | BRD4 (0.38) | BRD4BRD9KDM4ECYP2C9KDM6A | |
| SCHEMBL31748394 | 0.74 | KDM4E (0.55) | BRD4BRD9KDM4ECYP2C9KDM6A | |
| SCHEMBL19651995 | 0.74 | SIRT3 (0.39) | BRD4BRD9KDM4ECYP2C9KDM6A | |
| Hydrochloric Acid SCHEMBL28139132 | 0.73 | BRD4 (0.37) | BRD4BRD9KDM4ECYP2C9KDM6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3600312-A1 | PIPERIDINYL- AND PIPERAZINYL-SUBSTITUTED HETEROAROMATIC CARBOXAMIDES AS MODULATORS OF GPR6 | Takeda Pharmaceutical Company Limited (JP) | 2020-02-05 | — | — | EP | disclosed |
| WO-2018183145-A1 | PIPERIDINYL- AND PIPERAZINYL-SUBSTITUTED HETEROAROMATIC CARBOXAMIDES AS MODULATORS OF GPR6 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-10-04 | — | — | WO | disclosed |
| EP-1000123-B1 | USE OF REACTIVE DYES FOR DYEING HAIR | BASF SE (DE) | 2008-09-10 | — | — | EP | disclosed |
| EP-1124903-B1 | CATIONIC AZO-DYES | BASF AG (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6485527-B1 | Use of reactive dyes for dyeing hair | BASF AKTIENGESELLSCHAFT (DE) | 2002-11-26 | — | — | US | disclosed |
| EP-0929610-B1 | REACTIVE DYES WITH A HETEROCYCLIC ANCHOR | DYSTAR TEXTILFARBEN GMBH & CO (DE) | 2002-08-28 | — | — | EP | disclosed |
| US-6346609-B1 | DISAZO DYES OR POLYAZO DYES | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-12 | — | — | US | disclosed |
| EP-1027387-B1 | DOUBLE REACTIVE DYES | DYSTAR TEXTILFARBEN GMBH & CO (DE) | 2002-02-06 | — | — | EP | disclosed |
| EP-1124903-A1 | CATIONIC AZO-DYES | BASF AKTIENGESELLSCHAFT (DE) | 2001-08-22 | — | — | EP | disclosed |
| EP-0955342-B1 | Cationic azo dyes derived from aminobenzoic acid | BASF AG (DE) | 2001-07-11 | — | — | EP | disclosed |
| EP-0352682-B1 | Twice reactive dyes and benzyl compounds as their intermediary products | BASF AG (DE) | 1994-02-02 | — | — | EP | disclosed |
| US-5245020-A | Reactive dyes with two or three nitrogen-containing haloheterocycles as reactive system | BASF AKTIENGESELLSCHAFT (DE) | 1993-09-14 | — | — | US | disclosed |
| US-5241055-A | Use in cold pad-batch processing; fixing; fiber bonding; color- and washfastness; monoazo-, disazo-formazan, triphenyldioxazine and metal phthalocyanine dyes | BASF AKTIENGESELLSCHAFT (DE) | 1993-08-31 | — | — | US | disclosed |
| US-5231171-A | Dyeing or printing substrates such as cellulose | BASF AKTIENGESELLSCHAFT (DE) | 1993-07-27 | — | — | US | disclosed |
| US-5210187-A | Cotton or wool, wet fastness | BASF AKTIENGESELLSCHAFT (DE) | 1993-05-11 | — | — | US | disclosed |
| US-5149789-A | Triazine dyes | BASF AKTIENGESELLSCHAFT (DE) | 1992-09-22 | — | — | US | disclosed |
| EP-0492236-A1 | Reactive dyes with alkenylsulphonyl or alkinylsulphonyl groups serving as anchor | BASF Aktiengesellschaft (DE) | 1992-07-01 | — | — | EP | disclosed |
| EP-0433821-A1 | Reactive dyes having an anchor on basis of alkenylsulfonyl and benzyl compounds as their intermediates | BASF Aktiengesellschaft (DE) | 1991-06-26 | — | — | EP | disclosed |
| EP-0391264-A1 | Reactive dyes with two or three halogen-N-heterocycles as reactive groups | BASF Aktiengesellschaft (DE) | 1990-10-10 | — | — | EP | disclosed |
| EP-0352682-A2 | Twice reactive dyes and benzyl compounds as their intermediary products | BASF Aktiengesellschaft (DE) | 1990-01-31 | — | — | EP | disclosed |