Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | KDM6A | O15550 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28139132 | 0.98 | BRD4 (0.37) | BRD4BRD9KDM4EKDM6AKDM4A | |
| SCHEMBL866606 | 0.80 | ALDH1A1 (0.39) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL28668408 | 0.80 | KMT2A (0.38) | BRD4KDM4EKDM6AKDM4ACYP2C9 | |
| SCHEMBL4051027 | 0.78 | MEN1 (0.35) | BRD4BRD9KDM4ECYP2C19SMN1; SMN2 | |
| SCHEMBL25072434 | 0.78 | KDM4E (0.35) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL31201169 | 0.77 | PKM (0.36) | BRD4KDM4EKDM6AKDM4ACYP2C9 | |
| SCHEMBL16992853 | 0.77 | MAP2K1 (0.34) | BRD4KDM4EKDM6AKDM4ACYP2C9 | |
| SCHEMBL31710685 | 0.77 | AR (0.33) | BRD4BRD9KDM4EKDM6AKDM4A | |
| SCHEMBL11286998 | 0.75 | KDM4E (0.46) | BRD4KDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL4649779 | 0.75 | BRD4 (0.42) | BRD4BRD9KDM4EKDM6AKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106674201-A | Pyrrole compounds, method of preparing same and pharmaceutical compositions containing the compounds | 法国施维雅药厂 | 2017-05-17 | — | — | CN | claimed |
| EP-1896454-A1 | AMlNO-5-(5-MEMBERED)HETEROARYLIMIDAZOLONE COMPOUNDS AND THE USE THEREOF FOR -SECRETASE MODULATION | Wyeth a Corporation of the State of Delaware (US) | 2008-03-12 | — | — | EP | claimed |
| WO-2007005366-A1 | AMlNO-5-(5-MEMBERED)HETEROARYLIMIDAZOLONE COMPOUNDS AND THE USE THEREOF FOR β-SECRETASE MODULATION | WYETH (US) | 2007-01-11 | — | — | WO | claimed |
| US-12599582-B2 | Pyrrole compounds | ALIGOS THERAPEUTICS, INC. (US) | 2026-04-14 | — | — | US | disclosed |
| US-20230390242-A1 | PYRROLE COMPOUNDS | ALIGOS THERAPEUTICS, INC. | 2023-12-07 | — | — | US | disclosed |
| US-11771680-B2 | Pyrrole compounds | ALIGOS THERAPEUTICS, INC. (US) | 2023-10-03 | — | — | US | disclosed |
| US-20220071957-A1 | PYRROLE COMPOUNDS | EMORY UNIVERSITY | 2022-03-10 | — | — | US | disclosed |
| US-11191747-B2 | Pyrrole compounds | ALIGOS THERAPEUTICS, INC. (US) | 2021-12-07 | — | — | US | disclosed |
| US-20200323821-A1 | PYRROLE COMPOUNDS | EMORY UNIVERSITY | 2020-10-15 | — | — | US | disclosed |
| EP-3700911-A1 | NOVEL MACROCYCLIC DERIVATIVES, PROCESS FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier SAS (FR) | 2020-09-02 | — | — | EP | disclosed |
| EP-2491039-A1 | HETEROCYCLYL PYRAZOLOPYRIMIDINE ANALOGUES AS JAK INHIBITORS | Cellzome Limited (GB) | 2012-08-29 | — | — | EP | disclosed |
| WO-2011048082-A1 | HETEROCYCLYL PYRAZOLOPYRIMIDINE ANALOGUES AS JAK INHIBITORS | CELLZOME LIMITED (GB) | 2011-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230390242-A1 | PYRROLE COMPOUNDS | PKD1, ADCYAP1R1, PYCR1 | BRD4 1834/4885BRD9 2456/4885KDM4E 2319/4885 |
| US-12599582-B2 | Pyrrole compounds | PEF1, CYP4F8, CYP2C19 | BRD4 4152/4885BRD9 3234/4885KDM4E 1162/4885 |
| US-11771680-B2 | Pyrrole compounds | PKD1, ADCYAP1R1, PYCR1 | BRD4 1834/4885BRD9 2456/4885KDM4E 2319/4885 |
| US-20200323821-A1 | PYRROLE COMPOUNDS | PKD1, ADCYAP1R1, PYCR1 | BRD4 1834/4885BRD9 2456/4885KDM4E 2319/4885 |
| US-20220071957-A1 | PYRROLE COMPOUNDS | PKD1, ADCYAP1R1, PYCR1 | BRD4 1834/4885BRD9 2456/4885KDM4E 2319/4885 |
| US-11191747-B2 | Pyrrole compounds | PKD1, ADCYAP1R1, PYCR1 | BRD4 1834/4885BRD9 2456/4885KDM4E 2319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.