Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 4/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | KDM6A | O15550 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.35 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.34 |
| ▸ | TAF1 | P21675 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19726699 | 0.81 | CYP2C9 (0.37) | BRD4BRD9KDM4EKDM6AKDM4A | |
| SCHEMBL3061744 | 0.81 | LIPG (0.45) | BRD4BRD9KDM4EKDM6AKDM4A | |
| SCHEMBL1384364 | 0.78 | KDM4E (0.45) | SIRT3TDP1BRD4BRD9KDM4E | |
| SCHEMBL4649779 | 0.74 | BRD4 (0.42) | SIRT3TDP1BRD4BRD9KDM4E | |
| SCHEMBL9614829 | 0.74 | KDM4E (0.44) | KDM4EPARP1MAP2K1MAP2K2IRAK4 | |
| SCHEMBL12677164 | 0.74 | BRD4 (0.42) | BRD4BRD9KDM4EPARP1MAP2K1 | |
| SCHEMBL25072434 | 0.74 | KDM4E (0.35) | SIRT3TDP1KDM4EKDM6AKDM4A | |
| SCHEMBL20516021 | 0.72 | BRD4 (0.41) | BRD4BRD9KDM4EMAP2K1MAP2K2 | |
| SCHEMBL22723993 | 0.72 | BRD4 (0.50) | BRD4KDM4EPARP1ALDH1A1L3MBTL1 | |
| SCHEMBL1018603 | 0.71 | NNMT (0.47) | SIRT3TDP1BRD4KDM4EPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170340759-A1 | RADIO-PHARMACEUTICAL COMPLEXES | BAYER AS (NO) | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170340759-A1 | RADIO-PHARMACEUTICAL COMPLEXES | PTMS, THOP1, PHPT1 | SIRT3 1934/4885TDP1 765/4885BRD4 3547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.